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Selected Publications
2024
Adamantylglycine as a High-Affinity Peptide Label for Membrane Transport Monitoring and Regulation
Pramod M, Alnajjar MA, Schöpper SN, Schwarzlose T, Nau WM, Hennig A (2024)
Chem. Commun. Advance article
Cellular Uptake of Cell-Penetrating Peptides Activated by Amphiphilic p-Sulfonatocalix[4]arenes
Huang C, Liu YC, Oh H, Guo DS, Nau WM, Hennig A (2024)
Chem. Eur. J. e202400174.
Dual-color real-time chemosensing of a compartmentalized reaction network involving enzyme-induced membrane permeation of peptides
Jiang R, Nilam M, Hennig A, Nau WM (2024)
Adv. Mater. 36(4):2306922
Bright individuals: Applications of fluorescent protein-based reporter systems in single-cell cellular microbiology
Schulte M, Grotheer L, Hensel M (2024)
Mol Microbiol. Online ahead of print.
Tracing the substrate translocation mechanism in P-glycoprotein
Gewering T, Waghray D, Parey K, Jung H, Tran NNB, Zapata J, Zhao P, Chen H, Januliene D, Hummer G, Urbatsch I, Moeller A, Zhang Q (2023)
Elife 12:RP90174.
2023
Structure of the thrombopoietin-MPL receptor complex is a blueprint for biasing hematopoiesis
Tsutsumi N, Masoumi Z, James SC, Tucker JA, Winkelmann H, Grey W, Picton LK, Moss L, Wilson SC, Caveney NA, Jude KM, Gati C, Piehler J, Hitchcock IS, Garcia KC (2023)
Cell 186(19):4189-4203.e22.
Mechanisms of nonvesicular ceramide transport
Clausmeyer L, Fröhlich F (2023)
Contact (Thousand Oaks) 6:25152564231208250.
Why kiss-and-hop explains that tau does not stabilize microtubules and does not interfere with axonal transport (at physiological conditions)
Bakota L, Brandt R (2023)
Cytoskeleton (Hoboken) 81(1):47-52.
Conformational variability of cyanobacterial ChlI, the AAA+ motor of magnesium chelatase involved in chlorophyll biosynthesis
Shvarev D, Scholz AI, Moeller A (2023)
mBio 14(5)
The dynamin Vps1 mediates Atg9 transport to the sites of autophagosome formation
Arlt H, Raman B, Filali-Mouncef Y, Hu Y, Leytens A, Hardenberg R, Guimarães R, Kriegenburg F, Mari M, Smaczynska-de Rooij II, Ayscough KR, Dengjel J, Ungermann C, Reggiori F (2023)
Biol. Chem. 299(5):104712.
First-row d6 metal complex enables photon upconversion and initiates blue light-dependent polymerization with red light
Wang C, Wegeberg C, Wenger OS (2023)
Angew Chem Int Ed Engl. 62(43):e202311470.
ER-dependent membrane repair of mycobacteria-induced vacuole damage
Anand A, Mazur A-C, Rosell-Arevalo P, Franzkoch R, Breitsprecher L, Listian SA, Hüttel SV, Müller D, Schäfer DG, Vormittag S, Hilbi H, Maniak M, Gutierrez MG, Barisch C (2023)
mBio 14(5):e0094323.
Topographical surface patterning with block copolymer stamps
Guo L, Steinhart M (2023)
ScienceDirect, Applied Surface Science(639)
Different tether proteins of the same membrane contact site affect the localization and mobility of each other
Amado L, Cogan AP, González Montoro A (2023)
J Cell Sci 136(13):jcs260786.
Regulatory sites in the Mon1-Ccz1 complex control Rab5 to Rab7 transition and endosome maturation
Borchers AC, Janz M, Schäfer JH, Moeller A, Kümmel D, Paululat A, Ungermann C, Langemeyer L (2023) Proc Natl Acad Sci U S A 120(30):e2303750120.
Drosophila collagens in specialised extracellular matrices
Reinhardt M, Drechsler M, Paululat A (2023)
Biol Chem. 404(5):535-550.
The role of lysosomes in lipid homeostasis
Fröhlich F, González Montoro A (2023)
Biol. Chem. 404(5):455-465.
Molecular determinants of protein half-life in chloroplasts with focus on the Clp protease system
Winckler LI, Dissmeyer N (2023)
Biol. Chem. 404(5):499-511.
Determinants of synergistic cell-cell interactions in bacteria
Pauli B, Ajmera S, Kost C (2023)
Biol. Chem. 404(5):499-511
Pore-forming proteins: from pore assembly to structure by quantitative single-molecule imaging
Margheritis E, Kappelhoff S, Cosentino K (2023)
Int J Mol Sci 24(5):4528.
Manipulation of microvillar proteins during Salmonella enterica invasion results in brush border effacement and actin remodeling
Felipe-López A, Hansmeier N, Danzer C, Hensel M (2023)
Front Cell Infect Microbiol 13:1137062.
Mechanism of receptor assembly via the pleiotropic adipokine Leptin
Tsirigotaki A, Dansercoer A, Verschueren KHG, Marković I, Pollmann C, Hafer M, Felix J, Birck C, Van Putte W, Catteeuw D, Tavernier J, Fernando Bazan J, Piehler J, Savvides SN, Verstraete K (2023)
Nat. Struct. Mol. Biol. 30:551–563.
The dynamin Vps1 mediates Atg9 transport to the sites of autophagosome formation
Arlt H, Raman B, Filali-Mouncef Y, Hu Y, Leytens A, Hardenberg R, Guimarães R, Kriegenburg F, Mari M, Smaczynska-de Rooij II, Ayscough KR, Dengjel J, Ungermann C, Reggiori F (2023)
J Biol Chem 13:104712.
Special issue on “Cytoskeletal proteins in health and neurodegenerative disease: Concepts and methods”
Brandt R, Götz J (2023)
Brain Res Bull 198:50-52.
Real-time growth kinetics analysis of macromolecular assemblies in cells with single molecule resolution
Danial JSH, Jenner A, Garcia-Saez AJ, Cosentino K (2023)
J Phys Chem A 127(15):3490-3496
Loss of respiratory complex I subunit NDUFB10 affects complex I assembly and supercomplex formation
Arroum T, Borowski MT, Marx N, Schmelter F, Scholz M, Psathaki OE, Hippler M, Enriquez JA, Busch KB (2023)
Biol. Chem. 404(5):399-415.
An ERK-dependent molecular switch antagonizes fibrosis and promotes regeneration in spiny mice (Acomys)
Tomasso A, Koopmans T, Lijnzaad P, Bartscherer K, Seifert AW (2023)
Sci Adv 9(17):eadf2331.
When crystals flow
Tu CH, Steinhart M, Berger R, Kappl M, Butt HJ, Floudas G (2023)
Sci. Adv. 9(19):eadg8865
Early endosomes act as local exocytosis hubs to repair endothelial membrane damage
, , (2023)
Adv Sci (Weinh) e2300244.
Yeast Svf1 binds ceramides and contributes to sphingolipid metabolism at the ER cis-Golgi interface
Limar S, Körner C, Martínez-Montañés F, Stancheva VG, Wolf VN, Walter S, Miller EA, Ejsing CS, Galassi VV, Fröhlich F (2023)
J Cell Biol 222(5):e202109162.
Molecular changes in hippocampal energy metabolism in mice selectively bred for extremes in stress reactivity: Relevance of mitochondrial dysfunction for affective disorders
Rappeneau V, Koti P, Wilmes L, Widner-Andrae R, Busch K, Touma C (2023)
Eur J Neurosci. 58(2):2579-2602.
Interplay between calcium and sarcomeres directs cardiomyocyte maturation during regeneration
Nguyen PD, Gooijers I, Campostrini G, Verkerk AO, Honkoop H, Bouwman M, de Bakker DEM, Koopmans T, Vink A, Lamers GEM, Shakked A, Mars J, Mulder AA, Chocron S, Bartscherer K, Tzahor E, Mummery CL, de Boer TP, Bellin M, Bakkers J (2023)
Science 380(6646):758-764.
Yck3 casein kinase-mediated phosphorylation determines Ivy1 localization and function at endosomes and the vacuole
Grziwa S, Schäfer JH, Nicastro R, Arens A, De Virgilio C, Fröhlich F, Moeller A, Gao J, Langemeyer L, Ungermann C (2023)
J Cell Sci jcs.260889.
Flagella-mediated cytosolic motility of Salmonella enterica Paratyphi A aids in evasion of xenophagy but does not impact egress from host cells
Scharte F, Franzkoch R, Hensel M (2023)
Mol Microbiol 00, 1–18.
Multiple tethers of organelle contact sites are involved in α-synuclein toxicity in yeast
Del Vecchio M, Amado L, Cogan AP, Meert E, Rosseels J, Franssens V, Govers SK, Winderickx J, Montoro AG (2023)
Mol Biol Cell 34(8):ar84
Differentiation and function of cardiac valves in the adult Drosophila heart
Meyer C, Drechsler M, Meyer H, Paululat A (2023)
J Exp Biol jeb.245839.
Single-molecule fluorescent in situ hybridization (smFISH) on whole-mount planarians
Roovers EF, Bartscherer K (2023)
Schmidtea Mediterranea 2680:93–106.
Click-functionalization of silanized carbon nanotubes: from inorganic heterostructures to biosensing nanohybrids
Manoharan G, Bösel P, Thien J, Holtmannspötter M, Meingast L, Schmidt M, Eickmeier H, Haase M, Maultzsch J, Steinhart M, Wollschläger J, Palma M, Meyer C (2023)
Molecules 28(5):2161.
Dispersible SnO2 :Sb and TiO2 Nanocrystals After Calcination at High Temperature
Klein J, Philippi M, Alarslan F, Jähnichen T, Enke D, Steinhart M, Haase M (2023)
Small 19(10):e2207674.
Single molecule analyses reveal dynamics of Salmonella translocated effector proteins in host cell endomembranes
Göser V, Sander N, Schulte M, Scharte F, Franzkoch R, Liss V, Psathaki OE, Hensel M (2023)
Nat Commun 14(1):1240.
Setting up a data management infrastructure for bioimaging
Kunis S, Bernhardt K, Hensel M (2023)
Biol. Chem. 404(5):433-439.
Membrane damage and repair: a thin line between life and death
Barisch C, Holthuis J, Cosentino C (2023)
Biol. Chem. 404(5):467-490.
The role of lysosomes in lipid homeostasis
Fröhlich F, González Montoro A (2023)
Biol. Chem. 404(5):455-465.
Targeting of the Mon1-Ccz1 Rab guanine nucleotide exchange factor to distinct organelles by a synergistic protein and lipid code
Herrmann E, Langemeyer L, Auffarth K, Ungermann C, Kümmel D (2023)
J Biol Chem 102915.
Computational resolution in single molecule localization - impact of noise level and emitter density
Hockmann M, Kunis S, Kurre R (2023)
Biol. Chem. 404(5):427-43
Reversible live-cell labeling with retro-engineered HaloTags enables long-term high- and super-resolution imaging
Holtmannspötter M, Wienbeuker E, Dellmann T, Watrinet I, Garcia Saez AJ, Johnsson K, Kurre R, Piehler J (2023)
Angew Chem Int Ed Engl. 62(18):e202219050
Drosophila collagens in specialised extracellular matrices
Reinhardt M, Drechsler M, Paululat A (2023)
Biol. Chem. 404(5):535-550.
Lattice light-sheet microscopy and evaluation of dendritic transport in cultured hippocampal tissue reveal high variability in mobility of the KIF1A motor domain and entry into dendritic spines
Rierola M, Trushina NI, Holtmannspötter M, Kurre R, Bakota L (2023)
Brain Research Bulletin 149:13-22.
Neuronal stress granules as dynamic microcompartments: current concepts and open questions
Söhnel AC, Brandt R (2023)
Biol. Chem. 404(5):491-498
Plasma membrane topography governs the 3D dynamic localization of IgM B cell antigen receptor clusters
Saltukoglu D, Özdemir B, Holtmannspötter M, Reski R, Piehler J, Kurre R, Reth M (2023)
EMBO J e112030.
Facile repurposing of peptide-MHC-restricted antibodies for cancer immunotherapy
Yang X, Nishimiya D, Löchte S, Jude KM, Borowska M, Savvides CS, Dougan M, Su L, Zhao X, Piehler J, Garcia KC (2023)
Nat. Biotechnol. 41:932–943.
STAM and Hrs interact sequentially with IFN-α Receptor to control spatiotemporal JAK-STAT endosomal activation
Zanin N, Viaris de Lesegno C, Podkalicka J, Meyer T, Gonzalez Troncoso P, Bun P, Danglot L, Chmiest D, Urbé S, Piehler J, Blouin CM, Lamaze C (2023)
Nat Cell Biol. 25:425–438
2022
Trichome transcripts as efficiency control for synthetic biology and molecular farming
Becker R, Görner C, Reichman P, Dissmeyer N. (2022)
Methods Mol Biol. 2379:265-276.
The intracellular distribution of the small GTPase Rho5 and its dimeric guanidine nucleotide exchange factor Dck1/Lmo1 determine their function in oxidative stress response
Bischof L, Schweitzer F, Sterk CC, Heinisch JJ. (2022)
Int J Mol Sci. 23(14):7896.
IL-2 is inactivated by the acidic pH environment of tumors enabling engineering of a pH-selective mutein
Gaggero S, Martinez-Fabregas J, Cozzani A, Fyfe PK, Leprohon M, Yang J, Thomasen FE, Winkelmann H, Magnez R, Conti AG, Wilmes S, Pohler E, van Gijsel Bonnello M, Thuru X, Quesnel B, Soncin F, Piehler J, Lindorff-Larsen K, Roychoudhuri R, Moraga I, Mitra S. (2022)
Sci Immunol. 7(78):eade5686
Preparation of drosophila tissues and organs for transmission electron microscopy
Psathaki OE, Paululat A. (2022)
Methods Mol Biol. 2540:361-385
Common patterns of hydrolysis initiation in P-loop fold nucleoside triphosphatases
Kozlova MI, Shalaeva DN, Dibrova DV, Mulkidjanian AY (2022)
Biomolecules 12(10), 1345
Common mechanism of activated catalysis in P-loop fold nucleoside triphosphatases—United in diversity
Kozlova MI, Shalaeva DN, Dibrova DV, Mulkidjanian AY (2022)
Biomolecules 12(10), 1346
Biofunctional nanodot arrays in living cells uncover synergistic co-condensation of Wnt signalodroplets
Philippi M, Richter CP, Kappen M, Watrinet I, Miao Y, Runge M, Jorde L, Korneev S, Holtmannspötter M, Kurre R, Holthuis JCM, Garcia KC, Plückthun A, Steinhart M, Piehler J, You C (2022)
Small e2203723.
The ABC transporter MsbA adopts the wide inward-open conformation in E. coli cells
Galazzo L, Meier G, Januliene D, Parey K, De Vecchis D, Striednig B, Hilbi H, Schäfer LV, Kuprov I, Moeller A, Bordignon E, Seeger MA (2022)
Sci Adv. 8(41):eabn6845.
Super-resolution imaging and quantitative analysis of microtubule arrays in model neurons show that epothilone D increases the density but decreases the length and straightness of microtubules in axon-like processes
Conze C, Trushina NI, Holtmannspötter M, Rierola M, Attanasio S, Bakota L, Piehler J, Brandt R (2022)
Brain Res Bull. 190:234-243.
Reactive additive capillary stamping with double network hydrogel-derived aerogel stamps under solvothermal conditions
Alarslan F, Frosinn M, Ruwisch K, Thien J, Jähnichen T, Eckert L, Klein J, Haase M, Enke D, Wollschläger J, Beginn U, Steinhart M (2022)
ACS Appl. Mater. Interfaces 14(39):44992–45004
Pathogenic variants of sphingomyelin synthase SMS2 disrupt lipid landscapes in the secretory pathway
Sokoya T, Parolek J, Foged MM, Danylchuk DI, Bozan M, Sarkar B, Hilderink A, Philippi M, Botto LD, Terhal PA, Mäkitie O, Piehler J, Kim Y, Burd CG, Klymchenko AS, Maeda K, Holthuis JCM. (2022)
Elife. 11:e79278.
Structure of the HOPS tethering complex, a lysosomal membrane fusion machinery
Shvarev D, Schoppe J, König C, Perz A, Füllbrunn N, Kiontke S, Langemeyer L, Januliene D, Schnelle K, Kümmel D, Fröhlich F, Moeller A, Ungermann C. (2022)
Elife 11:e80901. Online ahead of print.
Preparation of drosophila tissues and organs for transmission electron microscopy
Psathaki OE, Paululat A. (2022)
Methods Mol Biol. 2540:361-385.
Proton-gradient-driven sensitivity enhancement of liposome-encapsulated supramolecular chemosensors
Nilam M, Karmacharya S, Nau WM, Hennig A. (2022)
Angew Chem Int Ed Engl. 61(35):e202207950.
Pathogenic autoantibodies to IFN-γ act through the impedance of receptor assembly and Fc-mediated response
Shih HP, Ding JY, Sotolongo Bellón J, Lo YF, Chung PH, Ting HT, Peng JJ, Wu TY, Lin CH, Lo CC, Lin YN, Yeh CF, Chen JB, Wu TS, Liu YM, Kuo CY, Wang SY, Tu KH, Ng CY, Lei WT, Tsai YH, Chen JH, Chuang YT, Huang JY, Rey FA, Chen HK, Chang TW, Piehler J, Chi CY, Ku CL. (2022)
J Exp Med. 219(9):e20212126.
Densely methylated DNA traps Methyl-CpG Binding Domain protein 2 but permits free diffusion by Methyl-CpG Binding Domain protein 3
Leighton GO, Irvin EM, Kaur P, Liu M, You C, Bhattaram D, Piehler J, Riehn R, Wang H, Pan H, Williams DC Jr. (2022)
Biol Chem. 26:102428.
An alliance between lipid transfer proteins and scramblases for membrane expansion
Holthuis JCM, Jahn H, Menon AK, Mizushima N. (2022)
Fac Rev. 11:22
Identification of a thyroid hormone binding site in Hsp90 with implications for its interaction with thyroid hormone receptor beta.
Fan L, Kishore A, Jansen-Olliges L, Wang D, Stahl F, Psathaki OE, Harre J, Warnecke A, Weder J, Preller M, Zeilinger C. (2022)
ACS Omega. 7(33):28932-28945.
Cvm1 is a component of multiple vacuolar contact sites required for sphingolipid homeostasis
Bisinski DD, Gomes Castro I, Mari M, Walter S, Fröhlich F, Schuldiner M, González Montoro A. (2022)
J Cell Biol. 221(8):e202103048.
Neprilysins regulate muscle contraction and heart function via cleavage of SERCA-inhibitory micropeptides
Schiemann R, Buhr A, Cordes E, Walter S, Heinisch JJ, Ferrero P, Milting H, Paululat A, Meyer H (2022)
Nat Commun. 13(1):4420
A Drosophila melanogaster model for TMEM43 related Arrhythmogenic right ventricular cardiomyopathy type 5
Klinke N, Meyer H, Ratnavadivel S, Reinhardt M, Heinisch JJ, Malmendal A, Milting H, Paululat A (2022)
Cell Mol Life Sci. 79(8):444
Organizing structural principles of the interleukin-17 ligand-receptor axis
Wilson SC, Caveney NA, Yen M, Pollmann C, Xiang X, Jude KM, Hafer M, Tsutsumi N, Piehler J, Garcia KC. (2022)
Nature, 609:622–629.
Vesicle transport: Exocyst follows PIP2 to tether membranes
Langemeyer L, Ungermann C. (2022)
Curr Biol. 32(13):R748-R750.
The HOPS tethering complex is required to maintain signaling endosome identity and TORC1 activity
Gao J, Nicastro R, Péli-Gulli M-P, Grziwa S, Chen Z, Kurre R, Piehler J, De Virgilio C, Fröhlich F, Ungermann C (2022)
J Cell Biol 221(5):e202109084.
Dissociation of β2m from MHC class I triggers formation of noncovalent, transient heavy chain dimers
Dirscherl C, Löchte S, Hein Z, Kopicki JD, Harders AR, Linden N, Karner A, Preiner J, Weghuber J, Garcia-Alai M, Uetrecht C, Zacharias M, Piehler J, Lanzerstorfer P, Springer S (2022)
J Cell Sci. jcs.259498
The yeast LYST homolog Bph1 is a Rab5 effector and prevents Atg8 lipidation at endosomes
Vargas Duarte P, Hardenberg R, Mari M, Walter S, Reggiori F, Fröhlich F, González Montoro A, Ungermann C (2022)
J Cell Sci. 135(8):jcs259421
Caspase-cleaved tau is senescence-associated and induces a toxic gain of function by putting a brake on axonal transport
Conze C, Rierola M, Trushina NI, Peters M, Janning D, Holzer M, Heinisch JJ, Arendt T, Bakota L, Brandt R. (2022)
Mol Psychiatry. Online ahead of print.
Intracellular Salmonella Paratyphi A is motile and differs in the expression of flagella-chemotaxis, SPI-1 and carbon utilization pathways in comparison to intracellular S. Typhimurium
Cohen H, Hoede C, Scharte F, Coluzzi C, Cohen E, Shomer I, Mallet L, Holbert S, Serre RF, Schiex T, Virlogeux-Payant I, Grassl GA, Hensel M, Chiapello H, Gal-Mor O (2022)
PLoS Pathog. 18(4):e1010425.
A lysosomal biogenesis map reveals the cargo spectrum of yeast vacuolar protein targeting pathways
Eising S, Esch B, Wälte M, Vargas Duarte P, Walter S, Ungermann C, Bohnert M, Fröhlich F (2022)
J Cell Biol. 221(4):e202107148.
Ca2+-activated sphingomyelin scrambling and turnover mediate ESCRT-independent lysosomal repair
Niekamp P, Scharte F, Sokoya T, Vittadello L, Kim Y, Deng Y, Südhoff E, Hilderink A, Imlau M, Clarke CJ, Hensel M, Burd CG, Holthuis JCM (2022)
Nature Communications 13:1875
Confocal real-time analysis of cutaneous platelet recruitment during immune-complex-mediated inflammation
Currie SM, Stegmeyer RI, Mildner K, Breitsprecher L, Zeuschner D, Psathaki OE, Schäfer K, Wilkens M, Volkery S, Nieswandt B, Vestweber D. (2022) J Invest Dermatol. 31:S0022-202X(22)00254-8.
Low membrane fluidity triggers lipid phase separation and protein segregation in living bacteria
Gohrbandt M, Lipski A, Grimshaw JW, Buttress JA, Baig Z, Herkenhoff B, Walter S, Kurre R, Deckers-Hebestreit G, Strahl H. (2022)
EMBO J. e109800.
Compartmentation and functions of sphingolipids
Körner C, Fröhlich F (2022)
Curr Opin Cell Biol. 74:104-111.
Monitoring and quantification of the dynamics of sress granule components in living cells by fluorescence decay after photoactivation
Söhnel AC, Trushina NI, Brandt R (2022)
Methods Mol Biol. 2428:243-259.
Structure of the Mon1-Ccz1 complex reveals molecular basis of membrane binding for Rab7 activation
Klink B, Herrmann E, Antoni C, Langemeyer L, Kiontke S, Gatsogiannis C, Ungermann C, Raunser S, Kümmel D (2022)
Proc Natl Acad Sci U S A. 119(6):e2121494119.
Bio-inspired adhesion control with liquids
Chen Y, Zhu Z, Steinhart M, Gorb SN. (2022)
iScience. 25(3):103864.
Four-color single-molecule imaging with engineered tags resolves the molecular architecture of signaling complexes in the plasma membrane
Bellón JS, Birkholz O, Richter CP, Eull F, Kenneweg H, Wilmes S, Rothbauer U, You C, Walter MR, Kurre R, Piehler J (2022)
Cell Reports Methods 2(2) 100165
Systematic Assessment of the Accuracy of Subunit Counting in Biomolecular Complexes Using Automated Single-Molecule Brightness Analysis
Danial JSH, Quintana Y, Ros U, Shalaby R, Margheritis EG, Chumpen Ramirez S, Ungermann C, Garcia-Saez AJ, Cosentino K (2022)
J Phys Chem Lett. 13(3):822-829
Frozen motion: how cryo-EM changes the way we look at ABC transporters
Shvarev D, Januliene D, Moeller A (2022)
Trends Biochem Sci. 47(2):136-148.
Surface modification of polycaprolactone scaffold with improved biocompatibility and controlled growth factor release for enhanced stem cell differentiation
Qin X, Wu Y, Liu S, Yang L, Yuan H, Cai S, Flesch J, Li Z, Tang Y, Li X, Zhuang Y, You C, Liu C, Yu C.
(2022)
Front Bioeng Biotechnol. 9:802311.
2021
Cationic ordering and its influence on the magnetic properties of co-rich cobalt ferrite thin films prepared by reactive solid phase epitaxy on Nb-doped SrTiO3(001)
Thien J, Bahlmann J, Alexander A, Ruwisch K, Rodewald J, Pohlmann T, Hoppe M, Alarslan F, Steinhart M, Altuncevahir B, Shafer P, Meyer C, Bertram F, Wollschläger J, Küpper K. (2021)
Materials (Basel). 15(1):46.
NIR-to-NIR imaging: extended excitation up to 2.2 μm using harmonic nanoparticles with a tunable hIGh EneRgy (TIGER) widefield microscope
Vittadello L, Klenen J, Koempe K, Kocsor L, Szaller Z, Imlau M (2021)
Nanomaterials (Basel). 11(12):3193.
Ischemic tolerance and cardiac repair in the spiny mouse (Acomys)
Koopmans T, van Beijnum H, Roovers EF, Tomasso A, Malhotra D, Boeter J, Psathaki OE, Versteeg D, van Rooij E, Bartscherer K (2021)
NPJ Regen Med. 6(1):78.
Phenolic resin dual-use stamps for capillary stamping and decal transfer printing
Guo L, Klein J, Thien J, Philippi M, Haase M, Wollschläger J, Steinhart M. (2021)
ACS Appl Mater Interfaces. 2021 13(41):49567-49579.
Single cell analyses reveal distinct adaptation of typhoidal and non-typhoidal Salmonella enterica serovars to intracellular lifestyle
Röder J, Felgner P, Hensel M. (2021)
Cell Microbiol. 23(10):e13374.
Micro-Meta App: an interactive tool for collecting microscopy metadata based on community specifications
Rigano A, Ehmsen S, Öztürk SU, Ryan J, Balashov A, Hammer M, Kirli K, Boehm U, Brown CM, Bellve K, Chambers JJ, Cosolo A, Coleman RA, Faklaris O, Fogarty KE, Guilbert T, Hamacher AB, Itano MS, Keeley DP, Kunis S, Lacoste J, Laude A, Ma WY, Marcello M, Montero-Llopis P, Nelson G, Nitschke R, Pimentel JA, Weidtkamp-Peters S, Park PJ, Alver BH, Grunwald D, & Strambio-De-Castillia C (2021)
Nat Methods. 18(12):1489-1495
Subunit exchange among endolysosomal tethering complexes is linked to contact site formation at the vacuole
Gonzáles Montoro A, Vargas Duarte P, Auffarth K, Walter S, Fröhlich F, & Ungermann C (2021)
Mol Biol Cell. 32(22):br14.
IFNAR1 and IFNAR2 play distinct roles in initiating type I interferon-induced JAK-STAT signaling and activating STATs
Shemesh M, Lochte S, Piehler J, & Schreiber G
Sci Signal (2021) Nov 23;14(710):eabe4627
Subunit exchange among endolysosomal tethering complexes is linked to contact site formation at the vacuole
González Montoro A, Duarte PV, Auffarth K, Walter S, Fröhlich F, Ungermann C
Mol Biol Cell (2021) Nov 18 32(22) mbc.E21-05-0227
Metabolic dissimilarity determines the establishment of cross-feeding interactions in bacteria
Giri S, Oña L, Waschina S, Shitut S, Yousif G, Kaleta C, Kost C
Curr Biol. (2021) Oct 27;S0960-9822(21)01408-1
Dendrite tapering actuates a self-organizing signaling circuit for stochastic filopodia initiation in neurons
Mancinelli G, Lamparter L, Nosov G, Saha T, Pawluchin A, Kurre R, Rasch C, Ebrahimkutty M, Klingauf J, & Galic M
Proc Natl Acad Sci U S A (2021) Oct 26;118(43):e2106921118
Flexible open conformation of the AP-3 complex explains its role in cargo recruitment at the Golgi
Schoppe J, Schubert E, Apelbaum A, Yavavli E, Birkholz O, Stephanowitz H, Han Y, Perz A, Hofnagel O, Liu F, Piehler J, Raunser S, Ungermann C
J Biol Chem. (2021) 101334
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Chavent M, Duncan AL, Rassam P, Birkholz O, Hélie J, Reddy T, Beliaev D, Hambly B, Piehler J, Kleanthous C, Sansom MSP
Nat Commun, 9, 2846 (2018)
Multi-functional DNA nanostructures that puncture and remodel lipid membranes into hybrid materials
Birkholz O, Burns JR, Richter CP, Psathaki OE, Howorka S, Piehler J
Nat Commun, 9, 1521 (2018)
Germanium Plasmon Enhanced Resonators for Label-Free Terahertz Protein Sensing
Bettenhausen M, Römer F, Witzigmann B, Flesch J, Kurre R, Korneev S, Piehler J, You C, Kazmierczak M, Guha S, Capellini G, Schröder T
Frequenz, 72, 113-122 (2018)
Near-native, site-specific and purification-free protein labeling for quantitative protein interaction analysis by MicroScale Thermophoresis
Bartoschik T, Galinec S, Kleusch C, Walkiewicz K, Breitsprecher D, Weigert S, Muller YA, You C, Piehler J, Vercruysse T, Daelemans D, Tschammer N
Scientific reports, 8, 4977 (2018)
A search for ceramide binding proteins using bifunctional lipid analogues yields CERT-related protein StarD7
Bockelmann S, Mina JGM, Korneev S, Hassan DG, Müller D, Hilderink A, Vlieg HC, Raijmakers R, Heck AJR, Haberkant P, and Holthuis JC
J Lipid Res,, 59, 515-530 (2018)
Defective cortex glia plasma membrane structure underlies light-induced epilepsy in cpes mutants
Kunduri G, Turner-Evans D, Konya Y, Izumi Y, Nagashima K, Lockett S, Holthuis J, Bamba T, Acharya U, Acharya JK
Proc Natl Acad Sci USA, 115, E8919-E8928 (2018)
Colloidal Crystals of NaYF4 Upconversion Nanocrystals Studied by Small-Angle X-Ray Scattering (SAXS)
Homann C, Bolze J, Haase M
Part Part Syst Charact, 1800391 (2018)
Colloidal LaPO4:Gd\(^{3+}\) nanocrystals: X-ray induced single line UV emission
Espinoza S, Juestel T, Haase M
Nanoscale 10, 22533-22540 (2018)
Deep Ultraviolet Emitting Scintillators for Biomedical Applications: The Hard Way of Downsizing LuPO4:Pr\(^{3+}\)
Espinoza S, Volhard MF, Kätker H, Jenneboer H, Uckelmann A, Haase M, Müller M , Purschke M, Jüstel T
Part Part Syst Charact, 1800282 (2018)
NaYF4:Yb,Er/NaYF4 core/shell nanocrystals with high upconversion luminescence quantum yield
Homann C, Krukewitt L, Frenzel F, Grauel B, Würth C , Resch-Genger U, Haase M
Angew Chem Int Ed, 57, 8765–8769 (2018), DOI
Angew Chem, 130, 8901–8905 (2018), DOI
Holographic performance of silicon polymer films based on photoswitchable molecules
Bourdon B, Bock S, Kijatkin C, Shumelyuk A, Imlau M
Optical Material Express 8(7), 1951-1967 (2018)
Nonlinear Optical Potassium Niobate Nanocrystals as Harmonic Markers: The Role of Precursors and Stoichiometry in Hydrothermal Synthesis
Wang Z, Kijatkin C, Urban A, Haase M, Imlau M and Kömpe K
Nanoscale, 10, 10713-10720 (2018)
2017
Ligand-induced type II interleukin-4 receptor dimers are sustained by rapid re-association within plasma membrane microcompartments
Richter D, Moraga I, Winkelmann H, Birkholz O, Wilmes S, Schulte M, Kraich M, Kenneweg H, Beutel O, Selenschik P, Paterok D, Gavutis M, Schmidt T, Garcia KC, Müller TD, Piehler J
Nat Commun, 8, 15976 (2017)
Magnetic control of cellular processes using biofunctional nanoparticles
Monzel C, Vicario C, Piehler J, Coppey M, Dahan M
Chemical science, 8, 7330-7338 (2017)
Engineered Ferritin for Magnetogenetic Manipulation of Proteins and Organelles Inside Living Cells
Liße D, Monzel C, Vicario C, Manzi J, Maurin I, Coppey M, Piehler J, Dahan M
Advanced materials, 29, 1700189 (2017)
Surrogate Wnt agonists that phenocopy canonical Wnt and beta-catenin signalling
Janda CY, Dang LT, You C, Chang J, de Lau W, Zhong ZA, Yan KS, Marecic O, Siepe D, Li X, Moody JD, Williams BO, Clevers H, Piehler J, Baker D, Kuo CJ, Garcia KC
Nature, 545, 234-237 (2017)
Binding of interferon reduces the force of unfolding for interferon receptor 1
Chuartzman SG, Nevo R, Waichman S, Shental D, Piehler J, Levy Y, Reich Z, Kapon R
PLoS One, 12, e0175413 (2017)
STAT2 is an essential adaptor in USP18-mediated suppression of type I interferon signaling
Arimoto KI, Löchte S, Stoner SA, Burkart C, Zhang Y, Miyauchi S, Wilmes S, Fan JB, Heinisch JJ, Li Z, Yan M, Pellegrini S, Colland F, Piehler J, Zhang DE
Nature structural & molecular biology, 24, 279-289 (2017)
ER residency of the ceramide phosphoethanolamine synthase SMSr relies on homotypic oligomerization mediated by its SAM domain
Cabukusta B, Kol M, Kneller L, Hilderink A, Bickert A, Mina JG, Korneev S, Holthuis JC
Sci Rep, 7, 41290 (2017)
Diverting CERT-mediated ceramide transport to mitochondria triggers Bax-dependent apoptosis
Jain A, Beutel O, Ebell K, Korneev S, and Holthuis JC
J Cell Sci 130, 360-371 (2017)
Switching head group selectivity in mammalian sphingolipid biosynthesis by active-site-engineering of sphingomyelin synthases
Kol M, Panatala R, Nordmann M, Swart L, van Suijlekom L, Cabukusta B, Hilderink A, Grabietz T, Mina JGM, Somerharju P, Korneev S, Tafesse FG, and Holthuis JC
J Lipid Res, 58, 962-973 (2017)
Nonlinear Diffuse fs-Pulse Reflectometry of Harmonic Upconversion Nanoparticles
Kijatkin C, Eggert J, Bock S, Berben D, Oláh L, Szaller Z, Kis Z and Imlau M
Photonics, 4(1), 11 (2017)
2016
Drosophila neprilysins control insulin signaling and food intake via cleavage of regulatory peptides
Hallier B, Schiemann R, Cordes E, Vitos-Faleato J, Walter S, Heinisch JJ, Malmendal A, Paululat A, Meyer H
Elife, (2016) Dec 6;5:e19430
Monitoring Changes in the Oligomeric State of a Candidate Endoplasmic Reticulum (ER) Ceramide Sensor by Single-molecule Photobleaching
Cabukusta B, Köhlen JA, Richter CP, You C, Holthuis JC
J Biol Chem, 291(47):24735–24746 (2016)
Functional protein micropatterning for drug design and discovery
You, C, and Piehler, J
Expert opinion on drug discovery, 11, 105-119 (2016)
Receptor dimer stabilization by hierarchical plasma membrane microcompartments regulates cytokine signaling
You C, Marquez-Lago TT, Richter CP, Wilmes S, Moraga I, Garcia KC, Leier A, Piehler J
Science advances, 2, e1600452 (2016)
Functional interplay between SA1 and TRF1 in telomeric DNA binding and DNA-DNA pairing
Lin J, Countryman P, Chen H, Pan H, Fan Y, Jiang Y, Kaur P, Miao W, Gurgel G, You C, Piehler J, Kad NM, Riehn R, Opresko PL, Smith S, Tao YJ, Wang H.
Nucleic acids research, 44, 6363-6376 (2016)
Bioinspired monolithic polymer microsphere arrays as generically anti-adhesive surfaces
Eichler-Volf A, Kovalev A, Wedeking T, Gorb EV, Xue L, You C, Piehler J, Gorb SN, Steinhart M
Bioinspiration & biomimetics, 11, 025002 (2016)
Engineered Upconversion Nanoparticles for Resolving Protein Interactions inside Living Cells
Drees C, Raj AN, Kurre R, Busch KB, Haase M, Piehler J
Angew Chem Int Ed Engl, 55, 11668-11672 (2016)
Single molecule super-resolution imaging of proteins in living Salmonella enterica using self-labelling enzymes
Barlag B, Beutel O, Janning D, Czarniak F, Richter CP, Kommnick C, Göser V, Kurre R, Fabiani F, Erhardt M, Piehler J, Hensel M
Scientific reports, 6, 31601 (2016)
Structure of the Tuberous Sclerosis Complex 2 (TSC2) N Terminus Provides Insight into Complex Assembly and Tuberous Sclerosis Pathogenesis
Zech R, Kiontke S, Mueller U, Oeckinghaus A, Kümmel D
J Biol Chem, 291, 20008 (2016)
The N-terminus of the floral Arabidopsis TGA transcription factor PERIANTHIA mediates redox-sensitive DNA-binding
Gutsche N and Zachgo S
PlosOne, 29; 11(4):e0153810 (2016)
