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Selected Publications


Dual-color real-time chemosensing of a compartmentalized reaction network involving enzyme-induced membrane permeation of peptides

Jiang R, Nilam M, Hennig A, Nau WM (2024)
Adv. Mater. 36(4):2306922

Bright individuals: Applications of fluorescent protein-based reporter systems in single-cell cellular microbiology

Schulte M, Grotheer L, Hensel M (2024)
Mol Microbiol. Online ahead of print.

Tracing the substrate translocation mechanism in P-glycoprotein

Gewering T, Waghray D, Parey K, Jung H, Tran NNB, Zapata J, Zhao P, Chen H, Januliene D, Hummer G, Urbatsch I, Moeller A, Zhang Q (2023)
Elife 12:RP90174.


Structure of the thrombopoietin-MPL receptor complex is a blueprint for biasing hematopoiesis

Tsutsumi N, Masoumi Z, James SC, Tucker JA, Winkelmann H, Grey W, Picton LK, Moss L, Wilson SC, Caveney NA, Jude KM, Gati C, Piehler J, Hitchcock IS, Garcia KC (2023)
Cell 186(19):4189-4203.e22.

Mechanisms of nonvesicular ceramide transport

Clausmeyer L, Fröhlich F (2023)
Contact (Thousand Oaks) 6:25152564231208250.

Why kiss-and-hop explains that tau does not stabilize microtubules and does not interfere with axonal transport (at physiological conditions)

Bakota L, Brandt R (2023)
Cytoskeleton (Hoboken) 81(1):47-52.

Conformational variability of cyanobacterial ChlI, the AAA+ motor of magnesium chelatase involved in chlorophyll biosynthesis

Shvarev D, Scholz AI, Moeller A (2023)
mBio 14(5)

The dynamin Vps1 mediates Atg9 transport to the sites of autophagosome formation

Arlt H, Raman B, Filali-Mouncef Y, Hu Y, Leytens A, Hardenberg R, Guimarães R, Kriegenburg F, Mari M, Smaczynska-de Rooij II, Ayscough KR, Dengjel J, Ungermann C, Reggiori F (2023)
Biol. Chem. 299(5):104712.

First-row d6 metal complex enables photon upconversion and initiates blue light-dependent polymerization with red light

Wang C, Wegeberg C, Wenger OS (2023)
Angew Chem Int Ed Engl. 62(43):e202311470.

ER-dependent membrane repair of mycobacteria-induced vacuole damage

Anand A, Mazur A-C, Rosell-Arevalo P, Franzkoch R, Breitsprecher L, Listian SA, Hüttel SV, Müller D, Schäfer DG, Vormittag S, Hilbi H, Maniak M, Gutierrez MG, Barisch C (2023)
mBio 14(5):e0094323.

Topographical surface patterning with block copolymer stamps

Guo L, Steinhart M (2023)
ScienceDirect, Applied Surface Science(639)

Different tether proteins of the same membrane contact site affect the localization and mobility of each other

Amado L, Cogan AP, González Montoro A (2023)
J Cell Sci 136(13):jcs260786.

Regulatory sites in the Mon1-Ccz1 complex control Rab5 to Rab7 transition and endosome maturation

Borchers AC, Janz M, Schäfer JH, Moeller A, Kümmel D, Paululat A, Ungermann C, Langemeyer L (2023) Proc Natl Acad Sci U S A 120(30):e2303750120. 

Drosophila collagens in specialised extracellular matrices

Reinhardt M, Drechsler M, Paululat A (2023)
Biol Chem. 404(5):535-550.

The role of lysosomes in lipid homeostasis

Fröhlich F, González Montoro A (2023)
Biol. Chem. 404(5):455-465.

Molecular determinants of protein half-life in chloroplasts with focus on the Clp protease system

Winckler LI, Dissmeyer N (2023)
Biol. Chem. 404(5):499-511.

Determinants of synergistic cell-cell interactions in bacteria

Pauli B, Ajmera S, Kost C (2023)
Biol. Chem. 404(5):499-511

Pore-forming proteins: from pore assembly to structure by quantitative single-molecule imaging

Margheritis E, Kappelhoff S, Cosentino K (2023)
Int J Mol Sci 24(5):4528.

Manipulation of microvillar proteins during Salmonella enterica invasion results in brush border effacement and actin remodeling

Felipe-López A, Hansmeier N, Danzer C, Hensel M (2023)
Front Cell Infect Microbiol 13:1137062.

Mechanism of receptor assembly via the pleiotropic adipokine Leptin

Tsirigotaki A, Dansercoer A, Verschueren KHG, Marković I, Pollmann C, Hafer M, Felix J, Birck C, Van Putte W, Catteeuw D, Tavernier J, Fernando Bazan J, Piehler J, Savvides SN, Verstraete K (2023)
Nat. Struct. Mol. Biol. 30:551–563.

The dynamin Vps1 mediates Atg9 transport to the sites of autophagosome formation

Arlt H, Raman B, Filali-Mouncef Y, Hu Y, Leytens A, Hardenberg R, Guimarães R, Kriegenburg F, Mari M, Smaczynska-de Rooij II, Ayscough KR, Dengjel J, Ungermann C, Reggiori F (2023)
J Biol Chem 13:104712.

Special issue on “Cytoskeletal proteins in health and neurodegenerative disease: Concepts and methods”

Brandt R, Götz J (2023)
Brain Res Bull 198:50-52.

Real-time growth kinetics analysis of macromolecular assemblies in cells with single molecule resolution

Danial JSH, Jenner A, Garcia-Saez AJ, Cosentino K (2023)
J Phys Chem A 127(15):3490-3496

Loss of respiratory complex I subunit NDUFB10 affects complex I assembly and supercomplex formation

Arroum T, Borowski MT, Marx N, Schmelter F, Scholz M, Psathaki OE, Hippler M, Enriquez JA, Busch KB (2023)
Biol. Chem. 404(5):399-415.

An ERK-dependent molecular switch antagonizes fibrosis and promotes regeneration in spiny mice (Acomys)

Tomasso A, Koopmans T, Lijnzaad P, Bartscherer K, Seifert AW (2023)
Sci Adv 9(17):eadf2331.

When crystals flow

Tu CH, Steinhart M, Berger R, Kappl M, Butt HJ, Floudas G (2023)
Sci. Adv. 9(19):eadg8865

Early endosomes act as local exocytosis hubs to repair endothelial membrane damage

Raj N, Greune L, Kahms M, Mildner K, Franzkoch R, Psathaki OE, Zobel T, Zeuschner D, Klingauf J, Gerke V (2023)
Adv Sci (Weinh) e2300244.

Yeast Svf1 binds ceramides and contributes to sphingolipid metabolism at the ER cis-Golgi interface

Limar S, Körner C, Martínez-Montañés F, Stancheva VG, Wolf VN, Walter S, Miller EA, Ejsing CS, Galassi VV, Fröhlich F (2023)
J Cell Biol 222(5):e202109162.

Molecular changes in hippocampal energy metabolism in mice selectively bred for extremes in stress reactivity: Relevance of mitochondrial dysfunction for affective disorders

Rappeneau V, Koti P, Wilmes L, Widner-Andrae R, Busch K, Touma C (2023)
Eur J Neurosci. 58(2):2579-2602.

Interplay between calcium and sarcomeres directs cardiomyocyte maturation during regeneration

Nguyen PD, Gooijers I, Campostrini G, Verkerk AO, Honkoop H, Bouwman M, de Bakker DEM, Koopmans T, Vink A, Lamers GEM, Shakked A, Mars J, Mulder AA, Chocron S, Bartscherer K, Tzahor E, Mummery CL, de Boer TP, Bellin M, Bakkers J (2023)
Science 380(6646):758-764.

Yck3 casein kinase-mediated phosphorylation determines Ivy1 localization and function at endosomes and the vacuole

Grziwa S, Schäfer JH, Nicastro R, Arens A, De Virgilio C, Fröhlich F, Moeller A, Gao J, Langemeyer L, Ungermann C (2023)
J Cell Sci jcs.260889.

Flagella-mediated cytosolic motility of Salmonella enterica Paratyphi A aids in evasion of xenophagy but does not impact egress from host cells

Scharte F, Franzkoch R, Hensel M (2023)
Mol Microbiol 00, 1–18.

Multiple tethers of organelle contact sites are involved in α-synuclein toxicity in yeast

Del Vecchio M, Amado L, Cogan AP, Meert E, Rosseels J, Franssens V, Govers SK, Winderickx J, Montoro AG (2023)
Mol Biol Cell 34(8):ar84

Differentiation and function of cardiac valves in the adult Drosophila heart

Meyer C, Drechsler M, Meyer H, Paululat A (2023)
J Exp Biol jeb.245839.

Single-molecule fluorescent in situ hybridization (smFISH) on whole-mount planarians

Roovers EF, Bartscherer K (2023)
Schmidtea Mediterranea 2680:93–106.

Click-functionalization of silanized carbon nanotubes: from inorganic heterostructures to biosensing nanohybrids

Manoharan G, Bösel P, Thien J, Holtmannspötter M, Meingast L, Schmidt M, Eickmeier H, Haase M, Maultzsch J, Steinhart M, Wollschläger J, Palma M, Meyer C (2023)
Molecules 28(5):2161.

Dispersible SnO2 :Sb and TiO2 Nanocrystals After Calcination at High Temperature

Klein J, Philippi M, Alarslan F, Jähnichen T, Enke D, Steinhart M, Haase M (2023)
Small 19(10):e2207674.

Single molecule analyses reveal dynamics of Salmonella translocated effector proteins in host cell endomembranes

Göser V, Sander N, Schulte M, Scharte F, Franzkoch R, Liss V, Psathaki OE, Hensel M (2023)
Nat Commun 14(1):1240.

Setting up a data management infrastructure for bioimaging

Kunis S, Bernhardt K, Hensel M (2023)
Biol. Chem. 404(5):433-439.

Membrane damage and repair: a thin line between life and death

Barisch C, Holthuis J, Cosentino C (2023)
Biol. Chem. 404(5):467-490.

The role of lysosomes in lipid homeostasis

Fröhlich F, González Montoro A (2023)
Biol. Chem. 404(5):455-465.

Targeting of the Mon1-Ccz1 Rab guanine nucleotide exchange factor to distinct organelles by a synergistic protein and lipid code

Herrmann E, Langemeyer L, Auffarth K, Ungermann C, Kümmel D (2023)
J Biol Chem 102915.

Computational resolution in single molecule localization - impact of noise level and emitter density

Hockmann M, Kunis S, Kurre R (2023)
Biol. Chem. 404(5):427-43

Reversible live-cell labeling with retro-engineered HaloTags enables long-term high- and super-resolution imaging

Holtmannspötter M, Wienbeuker E, Dellmann T, Watrinet I, Garcia Saez AJ, Johnsson K, Kurre R, Piehler J (2023)
Angew Chem Int Ed Engl. 62(18):e202219050

Drosophila collagens in specialised extracellular matrices

Reinhardt M, Drechsler M, Paululat A (2023)
Biol. Chem. 404(5):535-550.

Lattice light-sheet microscopy and evaluation of dendritic transport in cultured hippocampal tissue reveal high variability in mobility of the KIF1A motor domain and entry into dendritic spines

Rierola M, Trushina NI, Holtmannspötter M, Kurre R, Bakota L (2023)
Brain Research Bulletin 149:13-22.

Neuronal stress granules as dynamic microcompartments: current concepts and open questions

Söhnel AC, Brandt R (2023)
Biol. Chem. 404(5):491-498

Plasma membrane topography governs the 3D dynamic localization of IgM B cell antigen receptor clusters

Saltukoglu D, Özdemir B, Holtmannspötter M, Reski R, Piehler J, Kurre R, Reth M (2023)
EMBO J e112030.

Facile repurposing of peptide-MHC-restricted antibodies for cancer immunotherapy

Yang X, Nishimiya D, Löchte S, Jude KM, Borowska M, Savvides CS, Dougan M, Su L, Zhao X, Piehler J, Garcia KC (2023)
Nat. Biotechnol. 41:932–943.

STAM and Hrs interact sequentially with IFN-α Receptor to control spatiotemporal JAK-STAT endosomal activation

Zanin N, Viaris de Lesegno C, Podkalicka J, Meyer T, Gonzalez Troncoso P, Bun P, Danglot L, Chmiest D, Urbé S, Piehler J, Blouin CM, Lamaze C (2023)
Nat Cell Biol. 25:425–438


Trichome transcripts as efficiency control for synthetic biology and molecular farming

Becker R, Görner C, Reichman P, Dissmeyer N. (2022)
Methods Mol Biol. 2379:265-276.

The intracellular distribution of the small GTPase Rho5 and its dimeric guanidine nucleotide exchange factor Dck1/Lmo1 determine their function in oxidative stress response

Bischof L, Schweitzer F, Sterk CC, Heinisch JJ. (2022)
Int J Mol Sci. 23(14):7896.

IL-2 is inactivated by the acidic pH environment of tumors enabling engineering of a pH-selective mutein

Gaggero S, Martinez-Fabregas J, Cozzani A, Fyfe PK, Leprohon M, Yang J, Thomasen FE, Winkelmann H, Magnez R, Conti AG, Wilmes S, Pohler E, van Gijsel Bonnello M, Thuru X, Quesnel B, Soncin F, Piehler J, Lindorff-Larsen K, Roychoudhuri R, Moraga I, Mitra S. (2022)
Sci Immunol. 7(78):eade5686

Preparation of drosophila tissues and organs for transmission electron microscopy

Psathaki OE, Paululat A. (2022)
Methods Mol Biol. 2540:361-385

Common patterns of hydrolysis initiation in P-loop fold nucleoside triphosphatases

Kozlova MI, Shalaeva DN, Dibrova DV, Mulkidjanian AY (2022)
Biomolecules 12(10), 1345

Common mechanism of activated catalysis in P-loop fold nucleoside triphosphatases—United in diversity

Kozlova MI, Shalaeva DN, Dibrova DV, Mulkidjanian AY (2022)
Biomolecules 12(10), 1346

Biofunctional nanodot arrays in living cells uncover synergistic co-condensation of Wnt signalodroplets

Philippi M, Richter CP, Kappen M, Watrinet I, Miao Y, Runge M, Jorde L, Korneev S, Holtmannspötter M, Kurre R, Holthuis JCM, Garcia KC, Plückthun A, Steinhart M, Piehler J, You C (2022)
Small e2203723.

The ABC transporter MsbA adopts the wide inward-open conformation in E. coli cells

Galazzo L, Meier G, Januliene D, Parey K, De Vecchis D, Striednig B, Hilbi H, Schäfer LV, Kuprov I, Moeller A,  Bordignon E, Seeger MA (2022)
Sci Adv. 8(41):eabn6845.

Super-resolution imaging and quantitative analysis of microtubule arrays in model neurons show that epothilone D increases the density but decreases the length and straightness of microtubules in axon-like processes

Conze C, Trushina NI, Holtmannspötter M, Rierola M, Attanasio S, Bakota L, Piehler J, Brandt R (2022)
Brain Res Bull. 190:234-243.

Reactive additive capillary stamping with double network hydrogel-derived aerogel stamps under solvothermal conditions

Alarslan F, Frosinn M, Ruwisch K, Thien J, Jähnichen T, Eckert L, Klein J, Haase M, Enke D, Wollschläger J, Beginn U, Steinhart M (2022)
ACS Appl. Mater. Interfaces 14(39):44992–45004

Pathogenic variants of sphingomyelin synthase SMS2 disrupt lipid landscapes in the secretory pathway

Sokoya T, Parolek J, Foged MM, Danylchuk DI, Bozan M, Sarkar B, Hilderink A, Philippi M, Botto LD, Terhal PA, Mäkitie O, Piehler J, Kim Y, Burd CG, Klymchenko AS, Maeda K, Holthuis JCM. (2022)

Structure of the HOPS tethering complex, a lysosomal membrane fusion machinery

Shvarev D, Schoppe J, König C, Perz A, Füllbrunn N, Kiontke S, Langemeyer L, Januliene D, Schnelle K, Kümmel D, Fröhlich F, Moeller A, Ungermann C. (2022)
Elife 11:e80901. Online ahead of print.

Preparation of drosophila tissues and organs for transmission electron microscopy

Psathaki OE, Paululat A. (2022)
Methods Mol Biol. 2540:361-385.

Proton-gradient-driven sensitivity enhancement of liposome-encapsulated supramolecular chemosensors

Nilam M, Karmacharya S, Nau WM, Hennig A. (2022)
Angew Chem Int Ed Engl. 61(35):e202207950.

Pathogenic autoantibodies to IFN-γ act through the impedance of receptor assembly and Fc-mediated response

Shih HP, Ding JY, Sotolongo Bellón J, Lo YF, Chung PH, Ting HT, Peng JJ, Wu TY, Lin CH, Lo CC, Lin YN, Yeh CF, Chen JB, Wu TS, Liu YM, Kuo CY, Wang SY, Tu KH, Ng CY, Lei WT, Tsai YH, Chen JH, Chuang YT, Huang JY, Rey FA, Chen HK, Chang TW, Piehler J, Chi CY, Ku CL. (2022)
J Exp Med.

Densely methylated DNA traps Methyl-CpG Binding Domain protein 2 but permits free diffusion by Methyl-CpG Binding Domain protein 3

Leighton GO, Irvin EM, Kaur P, Liu M, You C, Bhattaram D, Piehler J, Riehn R, Wang H, Pan H, Williams DC Jr. (2022)
Biol Chem.

An alliance between lipid transfer proteins and scramblases for membrane expansion

Holthuis JCM, Jahn H, Menon AK, Mizushima N. (2022)
Fac Rev. 11:22

Identification of a thyroid hormone binding site in Hsp90 with implications for its interaction with thyroid hormone receptor beta.

Fan L, Kishore A, Jansen-Olliges L, Wang D, Stahl F, Psathaki OE, Harre J, Warnecke A, Weder J, Preller M, Zeilinger C. (2022)
ACS Omega.

Cvm1 is a component of multiple vacuolar contact sites required for sphingolipid homeostasis

Bisinski DD, Gomes Castro I, Mari M, Walter S, Fröhlich F, Schuldiner M, González Montoro A. (2022)
J Cell Biol. 221(8):e202103048.

Neprilysins regulate muscle contraction and heart function via cleavage of SERCA-inhibitory micropeptides

Schiemann R, Buhr A, Cordes E, Walter S, Heinisch JJ, Ferrero P, Milting H, Paululat A, Meyer H (2022)
Nat Commun
. 13(1):4420

A Drosophila melanogaster model for TMEM43 related Arrhythmogenic right ventricular cardiomyopathy type 5

Klinke N, Meyer H, Ratnavadivel S, Reinhardt M, Heinisch JJ, Malmendal A, Milting H, Paululat A (2022)
Cell Mol Life Sci.

Organizing structural principles of the interleukin-17 ligand-receptor axis

Wilson SC, Caveney NA, Yen M, Pollmann C, Xiang X, Jude KM, Hafer M, Tsutsumi N, Piehler J, Garcia KC. (2022)

Vesicle transport: Exocyst follows PIP2 to tether membranes

Langemeyer L, Ungermann C. (2022)
Curr Biol. 32(13):R748-R750.

The HOPS tethering complex is required to maintain signaling endosome identity and TORC1 activity

Gao J, Nicastro R, Péli-Gulli M-P, Grziwa S, Chen Z, Kurre R, Piehler J, De Virgilio C, Fröhlich F, Ungermann C (2022)
J Cell Biol 

Dissociation of β2m from MHC class I triggers formation of noncovalent, transient heavy chain dimers

Dirscherl C, Löchte S, Hein Z, Kopicki JD, Harders AR, Linden N, Karner A, Preiner J, Weghuber J, Garcia-Alai M, Uetrecht C, Zacharias M, Piehler J, Lanzerstorfer P, Springer S (2022)
J Cell Sci.

The yeast LYST homolog Bph1 is a Rab5 effector and prevents Atg8 lipidation at endosomes

Vargas Duarte P,  Hardenberg R, Mari M, Walter S, Reggiori F, Fröhlich F, González Montoro A, Ungermann C (2022)
J Cell Sci.

Caspase-cleaved tau is senescence-associated and induces a toxic gain of function by putting a brake on axonal transport

Conze C, Rierola M, Trushina NI, Peters M, Janning D, Holzer M, Heinisch JJ, Arendt T, Bakota L, Brandt R. (2022)
Mol Psychiatry.
Online ahead of print.

Intracellular Salmonella Paratyphi A is motile and differs in the expression of flagella-chemotaxis, SPI-1 and carbon utilization pathways in comparison to intracellular S. Typhimurium

Cohen H, Hoede C, Scharte F, Coluzzi C, Cohen E, Shomer I, Mallet L, Holbert S, Serre RF,  Schiex T, Virlogeux-Payant I, Grassl GA, Hensel M, Chiapello H, Gal-Mor O (2022)
PLoS Pathog.

A lysosomal biogenesis map reveals the cargo spectrum of yeast vacuolar protein targeting pathways

Eising S, Esch B, Wälte M, Vargas Duarte P, Walter S, Ungermann C, Bohnert M, Fröhlich F (2022)
J Cell Biol.

Ca2+-activated sphingomyelin scrambling and turnover mediate ESCRT-independent lysosomal repair

Niekamp P, Scharte F, Sokoya T, Vittadello L, Kim Y, Deng Y, Südhoff E, Hilderink A, Imlau M, Clarke CJ, Hensel M, Burd CG, Holthuis JCM (2022)
Nature Communications

Confocal real-time analysis of cutaneous platelet recruitment during immune-complex-mediated inflammation

Currie SM, Stegmeyer RI, Mildner K, Breitsprecher L, Zeuschner D, Psathaki OE, Schäfer K, Wilkens M, Volkery S, Nieswandt B, Vestweber D. (2022) J Invest Dermatol.  31:S0022-202X(22)00254-8.

Low membrane fluidity triggers lipid phase separation and protein segregation in living bacteria

Gohrbandt M, Lipski A, Grimshaw JW, Buttress JA, Baig Z, Herkenhoff B, Walter S, Kurre R, Deckers-Hebestreit G, Strahl H. (2022)
EMBO J. e109800.

Compartmentation and functions of sphingolipids

Körner C, Fröhlich F (2022)
Curr Opin Cell Biol.

Monitoring and quantification of the dynamics of sress granule components in living cells by fluorescence decay after photoactivation

Söhnel AC, Trushina NI, Brandt R (2022)
Methods Mol Biol
. 2428:243-259.

Structure of the Mon1-Ccz1 complex reveals molecular basis of membrane binding for Rab7 activation

Klink B, Herrmann E, Antoni C, Langemeyer L, Kiontke S, Gatsogiannis C, Ungermann C, Raunser S, Kümmel D (2022)
Proc Natl Acad Sci U S A.

Bio-inspired adhesion control with liquids

Chen Y, Zhu Z, Steinhart M, Gorb SN. (2022)
iScience. 25(3):103864.

Four-color single-molecule imaging with engineered tags resolves the molecular architecture of signaling complexes in the plasma membrane

Bellón JS, Birkholz O, Richter CP, Eull F, Kenneweg H, Wilmes S, Rothbauer U, You C, Walter MR, Kurre R, Piehler J (2022)
Cell Reports Methods
2(2) 100165

Systematic Assessment of the Accuracy of Subunit Counting in Biomolecular Complexes Using Automated Single-Molecule Brightness Analysis

Danial JSH, Quintana Y, Ros U, Shalaby R, Margheritis EG, Chumpen Ramirez S, Ungermann C, Garcia-Saez AJ, Cosentino K (2022)
J Phys Chem Lett
. 13(3):822-829

Frozen motion: how cryo-EM changes the way we look at ABC transporters

Shvarev D, Januliene D, Moeller A (2022)
Trends Biochem Sci
. 47(2):136-148.

Surface modification of polycaprolactone scaffold with improved biocompatibility and controlled growth factor release for enhanced stem cell differentiation

Qin X, Wu Y, Liu S, Yang L, Yuan H, Cai S, Flesch J, Li Z, Tang Y, Li X, Zhuang Y, You C, Liu C, Yu C.
Front Bioeng Biotechnol
. 9:802311.


Cationic ordering and its influence on the magnetic properties of co-rich cobalt ferrite thin films prepared by reactive solid phase epitaxy on Nb-doped SrTiO3(001)

Thien J, Bahlmann J, Alexander A, Ruwisch K, Rodewald J, Pohlmann T, Hoppe M, Alarslan F, Steinhart M, Altuncevahir B, Shafer P,  Meyer C, Bertram F, Wollschläger J, Küpper K. (2021)
Materials (Basel). 15(1):46.

NIR-to-NIR imaging: extended excitation up to 2.2 μm using harmonic nanoparticles with a tunable hIGh EneRgy (TIGER) widefield microscope

Vittadello L, Klenen J, Koempe K, Kocsor L, Szaller Z, Imlau M (2021)
Nanomaterials (Basel). 11(12):3193.

Ischemic tolerance and cardiac repair in the spiny mouse (Acomys)

Koopmans T, van Beijnum H, Roovers EF, Tomasso A, Malhotra D, Boeter J, Psathaki OE, Versteeg D, van Rooij E, Bartscherer K (2021)
NPJ Regen Med.

Phenolic resin dual-use stamps for capillary stamping and decal transfer printing

Guo L, Klein J, Thien J, Philippi M, Haase M, Wollschläger J, Steinhart M. (2021)
ACS Appl Mater Interfaces. 2021 13(41):49567-49579.

Single cell analyses reveal distinct adaptation of typhoidal and non-typhoidal Salmonella enterica serovars to intracellular lifestyle

Röder J, Felgner P, Hensel M. (2021)
Cell Microbiol. 23(10):e13374.

Micro-Meta App: an interactive tool for collecting microscopy metadata based on community specifications

Rigano A, Ehmsen S, Öztürk SU, Ryan J, Balashov A, Hammer M, Kirli K, Boehm U, Brown CM, Bellve K, Chambers JJ, Cosolo A, Coleman RA, Faklaris O, Fogarty KE, Guilbert T, Hamacher AB, Itano MS, Keeley DP, Kunis S, Lacoste J, Laude A, Ma WY, Marcello M, Montero-Llopis P, Nelson G, Nitschke R, Pimentel JA, Weidtkamp-Peters S, Park PJ, Alver BH, Grunwald D, & Strambio-De-Castillia C (2021)
Nat Methods. 18(12):1489-1495

Subunit exchange among endolysosomal tethering complexes is linked to contact site formation at the vacuole

Gonzáles Montoro A, Vargas Duarte P, Auffarth K, Walter S, Fröhlich F, & Ungermann C (2021)
Mol Biol Cell. 32(22):br14.

IFNAR1 and IFNAR2 play distinct roles in initiating type I interferon-induced JAK-STAT signaling and activating STATs

Shemesh M, Lochte S, Piehler J, & Schreiber G
Sci Signal (2021) Nov 23;14(710):eabe4627

Subunit exchange among endolysosomal tethering complexes is linked to contact site formation at the vacuole

González Montoro A, Duarte PV, Auffarth K, Walter S, Fröhlich F, Ungermann C
Mol Biol Cell (2021) Nov 18 32(22) mbc.E21-05-0227

Metabolic dissimilarity determines the establishment of cross-feeding interactions in bacteria

Giri S, Oña L, Waschina S, Shitut S, Yousif G, Kaleta C, Kost C
Curr Biol. (2021) Oct 27;S0960-9822(21)01408-1

Dendrite tapering actuates a self-organizing signaling circuit for stochastic filopodia initiation in neurons

Mancinelli G, Lamparter L, Nosov G, Saha T,  Pawluchin A, Kurre R, Rasch C, Ebrahimkutty M, Klingauf J, & Galic M
Proc Natl Acad Sci U S A (2021) Oct 26;118(43):e2106921118

Flexible open conformation of the AP-3 complex explains its role in cargo recruitment at the Golgi

Schoppe J, Schubert E, Apelbaum A, Yavavli E, Birkholz O, Stephanowitz H, Han Y, Perz A, Hofnagel O, Liu F, Piehler J, Raunser S, Ungermann C
J Biol Chem. (2021) 101334

A reference scale of cucurbit[7]uril binding affinities

Alnajja MA, Nau WM, & Hennig A
Org Biomol Chem (2021) Oct 14;19(39):8521-8529

Diffraction-Unlimited Photomanipulation at the Plasma Membrane via Specifically Targeted Upconversion Nanoparticles

Drees C, Rühl P, Czerny J, Chandra G, Bajorath J, Haase M, Heinemann SH, Piehler J
Nano Lett. (2021) Oct 13;21(19):8025-8034.

MDEmic: a metadata annotation tool to facilitate management of FAIR image data in the bioimaging community

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A Three-Dimensional Model of the Yeast Transmembrane Sensor Wsc1 Obtained by SMA-Based Detergent-Free Purification and Transmission Electron Microscopy

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Structure of the IFNγ receptor complex guides design of biased agonists

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A randomized multivariate matrix pencil method for superresolution microscopy

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MpTCP1 controls cell proliferation and redox processes in Marchantia polymorpha

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Close-packed silane nanodot arrays by capillary nanostamping coupled with heterocyclic silane ring opening

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Blocks in Tricarboxylic Acid Cycle of Salmonella enterica Cause Global Perturbation of Carbon Storage, Motility, and Host-Pathogen Interaction

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Topological control of cytokine receptor signaling induces differential effects in hematopoiesis

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MitoCLox: A Novel Mitochondria-Targeted Fluorescent Probe for Tracing Lipid Peroxidation

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ESEEM Reveals Bound Substrate Histidine in the ABC Transporter HisQMP\(_2\)

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Conformational dynamics of sensory rhodopsin II in nanolipoprotein and styrene-maleic acid lipid particles

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Proton leakage across lipid bilayers: Oxygen atoms of phospholipid ester linkers align water molecules into transmembrane water wires

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SERCA is critical to control the Bowditch effect in the heart

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APC/C\(^{Fzr}\) regulates cardiac and myoblast cell numbers, and plays a crucial role during myoblast fusion

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Drosophila pericardial nephrocyte ultrastructure changes during ageing

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Multi-color Localization Microscopy of Single Membrane Proteins in Organelles of Live Mammalian Cells

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Single-molecule imaging reveals dynamic biphasic partition of RNA-binding proteins in stress granules

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How nanoscale protein interactions determine the mesoscale dynamic organisation of bacterial outer membrane proteins

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Nat Commun, 9, 1521 (2018)

Germanium Plasmon Enhanced Resonators for Label-Free Terahertz Protein Sensing

Bettenhausen M, Römer F, Witzigmann B, Flesch J, Kurre R, Korneev S, Piehler J, You C, Kazmierczak M, Guha S, Capellini G, Schröder T
Frequenz, 72, 113-122 (2018)

Near-native, site-specific and purification-free protein labeling for quantitative protein interaction analysis by MicroScale Thermophoresis

Bartoschik T, Galinec S, Kleusch C, Walkiewicz K, Breitsprecher D, Weigert S, Muller YA, You C, Piehler J, Vercruysse T, Daelemans D, Tschammer N
Scientific reports, 8, 4977 (2018)

A search for ceramide binding proteins using bifunctional lipid analogues yields CERT-related protein StarD7

Bockelmann S, Mina JGM, Korneev S, Hassan DG, Müller D, Hilderink A, Vlieg HC, Raijmakers R, Heck AJR, Haberkant P, and Holthuis JC
J Lipid Res,, 59, 515-530 (2018)

Defective cortex glia plasma membrane structure underlies light-induced epilepsy in cpes mutants

Kunduri G, Turner-Evans D, Konya Y, Izumi Y, Nagashima K, Lockett S, Holthuis J, Bamba T, Acharya U, Acharya JK
Proc Natl Acad Sci USA, 115, E8919-E8928 (2018)

Colloidal Crystals of NaYF4 Upconversion Nanocrystals Studied by Small-Angle X-Ray Scattering (SAXS)

Homann C, Bolze J, Haase M
Part Part Syst Charact, 1800391 (2018)

Colloidal LaPO4:Gd\(^{3+}\) nanocrystals: X-ray induced single line UV emission

Espinoza S, Juestel T, Haase M
Nanoscale 10, 22533-22540 (2018)

Deep Ultraviolet Emitting Scintillators for Biomedical Applications: The Hard Way of Downsizing LuPO4:Pr\(^{3+}\)

Espinoza S, Volhard MF, Kätker H, Jenneboer H, Uckelmann A, Haase M, Müller M , Purschke M, Jüstel T
Part Part Syst Charact, 1800282 (2018)

NaYF4:Yb,Er/NaYF4 core/shell nanocrystals with high upconversion luminescence quantum yield

Homann C, Krukewitt L, Frenzel F, Grauel B, Würth C , Resch-Genger U, Haase M
Angew Chem Int Ed, 57, 8765–8769 (2018), DOI
Angew Chem, 130, 8901–8905 (2018), DOI

Holographic performance of silicon polymer films based on photoswitchable molecules

Bourdon B, Bock S, Kijatkin C, Shumelyuk A, Imlau M
Optical Material Express 8(7), 1951-1967 (2018)

Nonlinear Optical Potassium Niobate Nanocrystals as Harmonic Markers: The Role of Precursors and Stoichiometry in Hydrothermal Synthesis

Wang Z, Kijatkin C, Urban A, Haase M, Imlau M and Kömpe K
Nanoscale, 10, 10713-10720 (2018)


Ligand-induced type II interleukin-4 receptor dimers are sustained by rapid re-association within plasma membrane microcompartments

Richter D, Moraga I, Winkelmann H, Birkholz O, Wilmes S, Schulte M, Kraich M, Kenneweg H, Beutel O, Selenschik P, Paterok D, Gavutis M, Schmidt T, Garcia KC, Müller TD, Piehler J
Nat Commun, 8, 15976 (2017)

Magnetic control of cellular processes using biofunctional nanoparticles

Monzel C, Vicario C, Piehler J, Coppey M, Dahan M
Chemical science, 8, 7330-7338 (2017)

Engineered Ferritin for Magnetogenetic Manipulation of Proteins and Organelles Inside Living Cells

Liße D, Monzel C, Vicario C, Manzi J, Maurin I, Coppey M, Piehler J, Dahan M
Advanced materials, 29, 1700189 (2017)

Surrogate Wnt agonists that phenocopy canonical Wnt and beta-catenin signalling

Janda CY, Dang LT, You C, Chang J, de Lau W, Zhong ZA, Yan KS, Marecic O, Siepe D, Li X, Moody JD, Williams BO, Clevers H, Piehler J, Baker D, Kuo CJ, Garcia KC
Nature, 545, 234-237 (2017)

Binding of interferon reduces the force of unfolding for interferon receptor 1

Chuartzman SG, Nevo R, Waichman S, Shental D, Piehler J, Levy Y, Reich Z, Kapon R
PLoS One, 12, e0175413 (2017)

STAT2 is an essential adaptor in USP18-mediated suppression of type I interferon signaling

Arimoto KI, Löchte S, Stoner SA, Burkart C, Zhang Y, Miyauchi S, Wilmes S, Fan JB, Heinisch JJ, Li Z, Yan M, Pellegrini S, Colland F, Piehler J, Zhang DE
Nature structural & molecular biology, 24, 279-289 (2017)

ER residency of the ceramide phosphoethanolamine synthase SMSr relies on homotypic oligomerization mediated by its SAM domain

Cabukusta B, Kol M, Kneller L, Hilderink A, Bickert A, Mina JG, Korneev S, Holthuis JC
Sci Rep, 7, 41290 (2017)

Diverting CERT-mediated ceramide transport to mitochondria triggers Bax-dependent apoptosis

Jain A, Beutel O, Ebell K, Korneev S, and Holthuis JC
J Cell Sci 130, 360-371 (2017)

Switching head group selectivity in mammalian sphingolipid biosynthesis by active-site-engineering of sphingomyelin synthases

Kol M, Panatala R, Nordmann M, Swart L, van Suijlekom L, Cabukusta B, Hilderink A, Grabietz T, Mina JGM, Somerharju P, Korneev S, Tafesse FG, and Holthuis JC
J Lipid Res, 58, 962-973 (2017)

Nonlinear Diffuse fs-Pulse Reflectometry of Harmonic Upconversion Nanoparticles

Kijatkin C, Eggert J, Bock S, Berben D, Oláh L, Szaller Z, Kis Z and Imlau M
Photonics, 4(1), 11 (2017)


Drosophila neprilysins control insulin signaling and food intake via cleavage of regulatory peptides

Hallier B, Schiemann R, Cordes E, Vitos-Faleato J, Walter S, Heinisch JJ, Malmendal A, Paululat A, Meyer H
Elife, (2016) Dec 6;5:e19430

Monitoring Changes in the Oligomeric State of a Candidate Endoplasmic Reticulum (ER) Ceramide Sensor by Single-molecule Photobleaching

Cabukusta B, Köhlen JA, Richter CP, You C, Holthuis JC
J Biol Chem, 291(47):24735–24746 (2016)

Functional protein micropatterning for drug design and discovery

You, C, and Piehler, J
Expert opinion on drug discovery, 11, 105-119 (2016)

Receptor dimer stabilization by hierarchical plasma membrane microcompartments regulates cytokine signaling

You C, Marquez-Lago TT, Richter CP, Wilmes S, Moraga I, Garcia KC, Leier A, Piehler J
Science advances, 2, e1600452 (2016)

Functional interplay between SA1 and TRF1 in telomeric DNA binding and DNA-DNA pairing

Lin J, Countryman P, Chen H, Pan H, Fan Y, Jiang Y, Kaur P, Miao W, Gurgel G, You C, Piehler J, Kad NM, Riehn R, Opresko PL, Smith S, Tao YJ, Wang H.
Nucleic acids research, 44, 6363-6376 (2016)

Bioinspired monolithic polymer microsphere arrays as generically anti-adhesive surfaces

Eichler-Volf A, Kovalev A, Wedeking T, Gorb EV, Xue L, You C, Piehler J, Gorb SN, Steinhart M
Bioinspiration & biomimetics, 11, 025002 (2016)

Engineered Upconversion Nanoparticles for Resolving Protein Interactions inside Living Cells

Drees C, Raj AN, Kurre R, Busch KB, Haase M, Piehler J
Angew Chem Int Ed Engl, 55, 11668-11672 (2016)

Single molecule super-resolution imaging of proteins in living Salmonella enterica using self-labelling enzymes

Barlag B, Beutel O, Janning D, Czarniak F, Richter CP, Kommnick C, Göser V, Kurre R, Fabiani F, Erhardt M, Piehler J, Hensel M
Scientific reports, 6, 31601 (2016)

Structure of the Tuberous Sclerosis Complex 2 (TSC2) N Terminus Provides Insight into Complex Assembly and Tuberous Sclerosis Pathogenesis

Zech R, Kiontke S, Mueller U, Oeckinghaus A, Kümmel D
J Biol Chem, 291, 20008 (2016)

The N-terminus of the floral Arabidopsis TGA transcription factor PERIANTHIA mediates redox-sensitive DNA-binding

Gutsche N and Zachgo S
PlosOne, 29; 11(4):e0153810 (2016)