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Selected Publications
2022
Ca2+-activated sphingomyelin scrambling and turnover mediate ESCRT-independent lysosomal repair.
Niekamp P, Scharte F, Sokoya T, Vittadello L, Kim Y, Deng Y, Südhoff E, Hilderink A, Imlau M, Clarke CJ, Hensel M, Burd CG, Holthuis JCM (2022) Nature Communications 13:1875,
Compartmentation and functions of sphingolipids
Körner C, Fröhlich F (2022) Curr Opin Cell Biol. 74:104-111.
Structure of the Mon1-Ccz1 complex reveals molecular basis of membrane binding for Rab7 activation
Klink B, Herrmann E, Antoni C, Langemeyer L, Kiontke S, Gatsogiannis C, Ungermann C, Raunser S, Kümmel D (2022) Proc Natl Acad Sci U S A. 119(6):e2121494119.
Monitoring and quantification of the dynamics of sress granule components in living cells by fluorescence decay after photoactivation
Söhnel AC, Trushina NI, Brandt R (2022) Methods Mol Biol. 2428:243-259.
A lysosomal biogenesis map reveals the cargo spectrum of yeast vacuolar protein targeting pathways
Eising S, Esch B, Wälte M, Vargas Duarte P, Walter S, Ungermann C, Bohnert M, Fröhlich F (2022) J Cell Biol. 221(4):e202107148.
The yeast LYST homolog Bph1 is a Rab5 effector and prevents Atg8 lipidation at endosomes
Vargas Duarte P, Hardenberg R, Mari M, Walter S, Reggiori F, Fröhlich F, González Montoro A, Ungermann C (2022) J Cell Sci. 135(8):jcs259421
Intracellular Salmonella Paratyphi A is motile and differs in the expression of flagella-chemotaxis, SPI-1 and carbon utilization pathways in comparison to intracellular S. Typhimurium
Cohen H, Hoede C, Scharte F, Coluzzi C, Cohen E, Shomer I, Mallet L, Holbert S, Serre RF, Schiex T, Virlogeux-Payant I, Grassl GA, Hensel M, Chiapello H, Gal-Mor O (2022) PLoS Pathog. 18(4):e1010425.
Dissociation of β2m from MHC class I triggers formation of noncovalent, transient heavy chain dimers
Dirscherl C, Löchte S, Hein Z, Kopicki JD, Harders AR, Linden N, Karner A, Preiner J, Weghuber J, Garcia-Alai M, Uetrecht C, Zacharias M, Piehler J, Lanzerstorfer P, Springer S (2022) J Cell Sci. jcs.259498
The HOPS tethering complex is required to maintain signaling endosome identity and TORC1 activity
Gao J, Nicastro R, Péli-Gulli M-P, Grziwa S, Chen Z, Kurre R, Piehler J, De Virgilio C, Fröhlich F, Ungermann C (2022) J Cell Biol 221(5):e202109084.
Four-color single-molecule imaging with engineered tags resolves the molecular architecture of signaling complexes in the plasma membrane
Bellón JS, Birkholz O, Richter CP, Eull F, Kenneweg H, Wilmes S, Rothbauer U, You C, Walter MR, Kurre R, Piehler J. (2022) Cell Reports Methods 2(2) 100165
Surface modification of polycaprolactone scaffold with improved biocompatibility and controlled growth factor release for enhanced stem cell differentiation
Qin X, Wu Y, Liu S, Yang L, Yuan H, Cai S, Flesch J, Li Z, Tang Y, Li X, Zhuang Y, You C, Liu C, Yu C. Front Bioeng Biotechnol (2022) Jan 7;9:802311.
Frozen motion: how cryo-EM changes the way we look at ABC transporters
Shvarev D, Januliene D, Moeller A. Trends Biochem Sci (2022) Feb;47(2):136-148.
Low membrane fluidity triggers lipid phase separation and protein segregation in living bacteria
Gohrbandt M, Lipski A, Grimshaw JW, Buttress JA, Baig Z, Herkenhoff B, Walter S, Kurre R, Deckers-Hebestreit G, Strahl H. EMBO J (2022) Jan 17;e109800.
Systematic Assessment of the Accuracy of Subunit Counting in Biomolecular Complexes Using Automated Single-Molecule Brightness Analysis
Danial JSH, Quintana Y, Ros U, Shalaby R, Margheritis EG, Chumpen Ramirez S, Ungermann C, Garcia-Saez AJ, Cosentino K. J Phys Chem Lett (2022) Jan 27;13(3):822-829
2021
Ischemic tolerance and cardiac repair in the spiny mouse (Acomys)
Koopmans T, van Beijnum H, Roovers EF, Tomasso A, Malhotra D, Boeter J, Psathaki OE, Versteeg D, van Rooij E, Bartscherer K. NPJ Regen Med (2021) 6(1),78.
Single cell analyses reveal distinct adaptation of typhoidal and non-typhoidal Salmonella enterica serovars to intracellular lifestyle
Röder J, Felgner P, Hensel M. Cell Microbiol (2021) 23(10):e13374.
Micro-Meta App: an interactive tool for collecting microscopy metadata based on community specifications
Rigano A, Ehmsen S, Öztürk SU, Ryan J, Balashov A, Hammer M, Kirli K, Boehm U, Brown CM, Bellve K, Chambers JJ, Cosolo A, Coleman RA, Faklaris O, Fogarty KE, Guilbert T, Hamacher AB, Itano MS, Keeley DP, Kunis S, Lacoste J, Laude A, Ma WY, Marcello M, Montero-Llopis P, Nelson G, Nitschke R, Pimentel JA, Weidtkamp-Peters S, Park PJ, Alver BH, Grunwald D, & Strambio-De-Castillia C
Nat Methods (2021) Dec;18(12):1489-1495
Subunit exchange among endolysosomal tethering complexes is linked to contact site formation at the vacuole
Gonzáles Montoro A, Vargas Duarte P, Auffarth K, Walter S, Fröhlich F, & Ungermann C
Mol Biol Cell (2021) Dec 1;32(22):br14. doi: 10.1091/mbc.E21-05-0227
IFNAR1 and IFNAR2 play distinct roles in initiating type I interferon-induced JAK-STAT signaling and activating STATs
Shemesh M, Lochte S, Piehler J, & Schreiber G
Sci Signal (2021) Nov 23;14(710):eabe4627
Subunit exchange among endolysosomal tethering complexes is linked to contact site formation at the vacuole
González Montoro A, Duarte PV, Auffarth K, Walter S, Fröhlich F, Ungermann C
Mol Biol Cell (2021) Nov 18 32(22) mbc.E21-05-0227
Metabolic dissimilarity determines the establishment of cross-feeding interactions in bacteria
Giri S, Oña L, Waschina S, Shitut S, Yousif G, Kaleta C, Kost C
Curr Biol. (2021) Oct 27;S0960-9822(21)01408-1
Dendrite tapering actuates a self-organizing signaling circuit for stochastic filopodia initiation in neurons
Mancinelli G, Lamparter L, Nosov G, Saha T, Pawluchin A, Kurre R, Rasch C, Ebrahimkutty M, Klingauf J, & Galic M
Proc Natl Acad Sci U S A (2021) Oct 26;118(43):e2106921118
Flexible open conformation of the AP-3 complex explains its role in cargo recruitment at the Golgi
Schoppe J, Schubert E, Apelbaum A, Yavavli E, Birkholz O, Stephanowitz H, Han Y, Perz A, Hofnagel O, Liu F, Piehler J, Raunser S, Ungermann C
J Biol Chem. (2021) 101334
A reference scale of cucurbit[7]uril binding affinities
Alnajja MA, Nau WM, & Hennig A
Org Biomol Chem (2021) Oct 14;19(39):8521-8529
Diffraction-Unlimited Photomanipulation at the Plasma Membrane via Specifically Targeted Upconversion Nanoparticles
Drees C, Rühl P, Czerny J, Chandra G, Bajorath J, Haase M, Heinemann SH, Piehler J
Nano Lett. (2021) Oct 13;21(19):8025-8034.
MDEmic: a metadata annotation tool to facilitate management of FAIR image data in the bioimaging community
Kunis S, Hänsch S, Schmidt C, Wong F, Strambio-De-Castillia C, Weidtkamp-Peters S
Nature Methods (2021) Oct 11 doi.org/10.1038/s41592-021-01288-z
QUAREP-LiMi: A community-driven initiative to establish guidelines for quality assessment and reproducibility for instruments and images in light microscopy
Nelson G, Boehm U, Bagley S, Bajcsy P, Bischof J, Brown CM, Dauphin A, Dobbie IM, Eriksson JE, Faklaris O, Fernandez-Rodriguez J, Ferrand A, Gelman L, Gheisari A, Hartmann H, Kukat C, Laude A, Mitkovski M, Munck S, North AJ, Rasse TM, Resch-Genger U, Schuetz LC, Seitz A, Strambio-De-Castillia C, Swedlow JR, Alexopoulos I, Aumayr K, Avilov S, Bakker G-J, Bammann RR, Bassi A, Beckert H, Beer S, Belyaev Y, Bierwagen J, Birngruber KA, Bosch M, Breitlow J, Cameron LA, Chalfoun J, Chambers JJ, Chen C-L, Conde-Sousa E, Corbett AD, Cordelieres FP, Del Nery E, Dietzel R, Eismann F, Fazeli E, Felscher A, Fried H, Gaudreault N, Goh WI , Guilbert T, Hadleigh R, Hemmerich P, Holst GA, Itano MS, Jaffe CB, Jambor HK, Jarvis SC, Keppler A, Kirchenbuechler D, Kirchner M, Kobayashi N, Krens G, Kunis S, Lacoste J, Marcello M, Martins GG, Metcalf DJ, Mitchell CA, Moore J, Mueller T, Nelson MS, Ogg S, Onami S, Palmer AL, Paul-Gilloteaux P, Pimentel JA, Plantard L, Podder S, Rexhepaj E, Royon A, Saari MA, Schapman D, Schoonderwoert V, Schroth-Diez B, Schwartz S, Shaw M, Spitaler M, Stoeckl MT, Sudar D, Teillon J, Terjung S, Thuenauer R, Wilms CD, Wright GD, & Nitschke R
J Microsc (2021) Oct;284(1):56-73.
Flexible open conformation of the AP-3 complex explains its role in cargo recruitment at the Golgi
Schoppe J, Schubert E, Apelbaum A, Yavavli E, Birkholz O, Stephanowitz H, Han Y, Perz A, Hofnagel O, Liu F, Piehler J, Raunser S, & Ungermann C
J Biol Chem 297 (2021), 101334
The small GTPase KlRho5 responds to oxidative stress and affects cytokinesis
Musielak M, Sterk CC, Schubert F, Meyer C, Paululat A, Heinisch JJ
J Cell Sci. (2021), Sep 15;134(18):jcs258301
Obligate cross-feeding expands the metabolic niche of bacteria
Oña L, Giri G, Avermann N, Kreienbaum M, Thormann KM, Kost C
Nat Ecol Evol. (2021) Sep;5(9):1224-1232
TSC1 binding to lysosomal PIPs is required for TSC complex translocation and mTORC1 regulation
Fitzian K, Brückner A, Brohée L, Zech R, Antoni C, Kiontke S, Gasper R, Linard Matos AL, Beel S, Wilhelm S, Gerke V, Ungermann C, Nellist M, Raunser S, Demetriades C, Oeckinghaus A, & Kümmel D
Mol Cell (2021), Jul 1 81(13):2705-2721
Who’s in control? Principles of Rab GTPase activation in endolysosomal membrane trafficking and beyond
Borchers AC, Langemeyer L, & Ungermann C
J Cell Biol (2021) 220 (9): e202105120
Apoptosis-inducing anti-HER2 agents operate through oligomerization-induced receptor immobilization
Stüber JC, Richter CP, Sotolongo Bellón J, Schwill M, König I, Schuler B, Piehler J, Plückthun A
Commun Biol, (2021) Jun 21;4(1):762
In-vivo tracking of harmonic nanoparticles: a study based on a TIGER widefield microscope
Vittadello L, Kijatkin C, Klenen J, Dzikonski D, Kömpe K, Meyer C, Paululat A, Imlau M
Optical Materials Express, (2021) 11, 1953-1969
Engineering an anti-HER2 biparatopic antibody with a multimodal mechanism of action
Kast F, Schwill M, Stüber JC, Pfundstein S, Nagy-Davidescu G, Rodríguez JMM, Seehusen F, Richter CP, Honegger A, Hartmann KP, Weber TG, Kroener F, Ernst P, Piehler J, Plückthun A
Nat Commun, (2021) Jun 18;12(1):3790
Evaluation of DIBMA nanoparticles of variable size and anionic lipid content as tools for the structural and functional study of membrane proteins
Voskoboynikova N, Margheritis EG, Kodde F, Rademacher M, Schowe M, Budke-Gieseking A, Psathaki OE, Steinhoff HJ, Cosentino K
Biochim Biophys Acta Biomembr, (2021) Jun 1;1863(6):183588
TSC1 binding to lysosomal PIPs is required for TSC complex translocation and mTORC1 regulation
Fitzian K, Brückner A, Brohée L, Zech R, Antoni C, Kiontke S, Gasper R, Linard Matos AL, Beel S, Wilhelm S, Gerke V, Ungermann C, Nellist M, Raunser S, Demetriades C, Oeckinghaus A, Kümmel D
Mol Cell, (2021) Apr 30:S1097-2765(21)00324-5
Lipid Dynamics in Diisobutylene-Maleic Acid (DIBMA) Lipid Particles in Presence of Sensory Rhodopsin II
Voskoboynikova N, Orekhov P, Bozdaganyan M, Kodde F, Rademacher M, Schowe M, Budke-Gieseking A, Brickwedde B, Psathaki OE, Mulkidjanian AY, Cosentino K, Shaitan KV, Steinhoff HJ
Int J Mol Sci, (2021) Mar 4;22(5):2548
The protected physiological state of intracellular Salmonella enterica persisters reduces host cell-imposed stress
Schulte M, Olschewski K, Hensel M
Commun Biol, (2021) May 4;4(1):520
Calibration of cell-intrinsic interleukin-2 response thresholds guides design of a regulatory T cell biased agonist
Glassman CR, Su L, Majri-Morrison SS, Winkelmann H, Mo F, Li P, Pérez-Cruz M, Ho PP, Koliesnik I, Nagy N, Hnizdilova T, Picton LK, Kovar M, Bollyky P, Steinman L, Meyer E, Piehler J, Leonard WJ, Garcia KC
Elife, (2021) May 18;10:e65777
Biofunctionalization of carbon nanotubes for reversible site-specific protein immobilization
Jorde L, Li Z, Pöppelwerth A, Piehler J, You C, Meyer C
Journal of Applied Physics, (2021) 129, 094302
Competitive binding of STATs to receptor phospho-Tyr motifs accounts for altered cytokine responses
Wilmes S, Jeffrey PA, Martinez-Fabregas J, Hafer M, Fyfe PK, Pohler E, Gaggero S, López-García M, Lythe G, Taylor C, Guerrier T, Launay D, Mitra S, Piehler J, Molina-París C, Moraga I
Elife, (2021) Apr 19;10:e66014
TSC1 binding to lysosomal PIPs is required for TSC complex translocation and mTORC1 regulation
Fitzian K, Brückner A, Brohée L, Zech R, Antoni C, Kiontke S, Gasper R, Linard Matos AL, Beel S, Wilhelm S, Gerke V, Ungermann C, Nellist M, Raunser S, Demetriades C, Oeckinghaus A, Kümmel D
Mol Cell, (2021) Apr 30:S1097-2765(21)00324-5
Fluorescent protein-based reporters reveal stress response of intracellular Salmonella enterica at level of single bacterial cells
Schulte M, Olschewski K, Hensel M
Cell Microbiol, (2021) Mar;23(3):e13293
n-type Ge/Si antennas for THz sensing
Chavarin CA, Hardt E, Gruessing S, Skibitzki O, Costina I, Spirito D, Seifert W, Klesse W, Manganelli CL, You C, Flesch J, Piehler J, Missori M, Baldassarre L, Witzigmann B, Capellini G
Opt Express, (2021) Mar 1;29(5):7680-7689
Correlative Light and Scanning Electron Microscopy to Study Interactions of Salmonella enterica with Polarized Epithelial Cell Monolayers
Kommnick C, Hensel M
Methods Mol Biol, (2021) J2182:103-115
Three-Dimensional Interfacing of Cells with Hierarchical Silicon Nano/Microstructures for Midinfrared Interrogation of In Situ Captured Proteins
Flesch J, Bettenhausen M, Kazmierczak M, Klesse WM, Skibitzki O, Psathaki OE, Kurre R, Capellini G, Guha S, Schroeder T, Witzigmann B, You C, Piehler J
ACS Appl Mater Interfaces, (2021) Feb 11
Self-Labeling Enzyme Tags for Translocation Analyses of Salmonella Effector Proteins
Göser V, Hensel M
Methods Mol Biol, (2021) 2182:67-82
Short Photoswitchable Ceramides Enable Optical Control of Apoptosis
Morstein J, Kol M, Novak AJE, Feng S, Khayyo S, Hinnah K, Li-Purcell N, Pan G, Williams BM, Riezman H, Atilla-Gokcumen GE, Holthuis JCM, Trauner D
ACS Chem Biol, (2021) Mar 19;16(3):452-456
A Three-Dimensional Model of the Yeast Transmembrane Sensor Wsc1 Obtained by SMA-Based Detergent-Free Purification and Transmission Electron Microscopy
Voskoboynikova N, Karlova M, Kurre R, Mulkidjanian AY, Shaitan KV, Sokolova OS, Steinhoff HJ, Heinisch JJ
J Fungi (Basel), (2021) Feb 5;7(2):118
Zn\(^{2+}\) Intoxication of Mycobacterium marinum during Dictyostelium discoideum Infection Is Counteracted by Induction of the Pathogen Zn\(^{2+}\) Exporter CtpC
Hanna N, Koliwer-Brandl H, Lefrançois LH, Kalinina V, Cardenal-Muñoz E, Appiah J, Leuba F, Gueho A, Hilbi H, Soldati T, Barisch C
mBio, (2021) Feb 2;12(1):e01313-20
Nanoscopic anatomy of dynamic multi-protein complexes at membranes resolved by graphene-induced energy transfer
Füllbrunn N, Li Z, Jorde L, Richter CP, Kurre R, Langemeyer L, Yu C, Meyer C, Enderlein J, Ungermann C, Piehler J, You C
Elife, (2021) Jan 29;10:e62501
Sphingomyelin Biosynthesis Is Essential for Phagocytic Signaling during Mycobacterium tuberculosis Host Cell Entry
Niekamp P, Guzman G, Leier HC, Rashidfarrokhi A, Richina V, Pott F, Barisch C, Holthuis JCM, Tafesse FG
mBio, (2021) Jan 26;12(1):e03141-20
TORC1 Determines Fab1 Lipid Kinase Function at Signaling Endosomes and Vacuoles
Chen Z, Malia PC, Hatakeyama R, Nicastro R, Hu Z, Péli-Gulli MP, Gao J, Nishimura T, Eskes E, Stefan CJ, Winderickx J, Dengjel J, De Virgilio C, Ungermann C
Curr Biol,(2021) Jan 25;31(2):297-309.e8
Membrane Permeability and Its Activation Energies in Dependence on Analyte, Lipid, and Phase Type Obtained by the Fluorescent Artificial Receptor Membrane Assay
Nilan M, Collin S, Karmacharya S. Hennig A, & Nau WM
ACS Sens (2021) Jan 22;6(1):175-182
Tuning MPL signaling to influence hematopoietic stem cell differentiation and inhibit essential thrombocythemia progenitors
Cui L, Moraga I, Lerbs T, Van Neste C, Wilmes S, Tsutsumi N, Trotman-Grant AC, Gakovic M, Andrews S, Gotlib J, Darmanis S, Enge M, Quake S, Hitchcock IS, Piehler J, Garcia KC, Wernig G
Proc Natl Acad Sci USA, (2021) Jan 12;118(2):e2017849118 (2021)
Capillary Stamping of Functional Materials: Parallel Additive Substrate Patterning without Ink Depletion
Runge M, Hübner H, Grimm A, Manoharan G, Wieczorek R, Philippi M, Harneit W, Meyer C, Enke D, Gallei M, Steinhart M
Advanced Materials Interfaces, (2021) 8, 2001911
2020
Interaction of Cucurbit[7]uril with protease substrates: application to nanosecond time-resolved fluorescence assays
Hennig A, Nau WM
Front Chem (2020) Sep 10
Parallelized Manipulation of Adherent Living Cells by Magnetic Nanoparticles-Mediated Forces
Bongaerts M, Aizel K, Secret E, Jan A, Nahar T, Raudzus F, Neumann S, Telling N, Heumann R, Siaugue JM, Menager C, Fresnais J, Villard C, El Haj A, Piehler J, Gates MA, & Coppey M
International journal of molecular sciences, 21 (2020)
Na1.5-x/2Gd1.5-x/2SrxF6 nanocrystals: Growth, size control and shell formation on β-NaCeF\(_{4}\):Tb core particles
Wehmeier J, Haase M
CrystEngComm, (2020) 22, 8036-8044
Engineered IL-10 variants elicit potent immunomodulatory effects at low ligand doses
Gorby C, Sotolongo Bellon J, Wilmes S, Warda W, Pohler E, Fyfe PK, Cozzani A, Ferrand C, Walter MR, Mitra S, Piehler J, & Moraga I
Sci Signal, 13, 649 (2020)
Towards a mathematical model for single molecule structured illumination microscopy
Hockmann M, Kunis S, and Kurre R
Proc Appl Math Mech, (2020)
Function of the SNARE Ykt6 on autophagosomes requires the Dsl1 complex and the Atg1 kinase complex
Gao J, Kurre R, Rose J, Walter S, Fröhlich F, Piehler J, Reggiori F, Ungermann C
EMBO Rep, (2020) Oct 7:e50733
Magnetic and Electronic Properties of Highly Mn-Doped β-NaGdF\(_{4}\) and β-NaEuF\(_{4}\) Nanoparticles with a Narrow Size Distribution
Schneider L, Wehmeier J, Wiedwald U, Rodewald J, Galakhov VR, Udintseva MS, Mesilov V, Radu F, Luo C, Klare JP, Steinhoff H-J, Haase M, Kuepper K
J Phys Chem C, (2020) 124, 33, 18194–18202
On the condition number of Vandermonde matrices with pairs of nearly-colliding nodes
Kunis S and Nagel D
Numer Algorithms, (2020)
On the smallest singular value of multivariate Vandermonde matrices with clustered nodes
Kunis S and Nagel D
Linear Algebra Appl, (2020) 604, 1-20
Size-Controlled Growth of β-NaGdF4 and β-NaGdF\(_{4}\):Yb,Er Nanocrystals: The Influence of the Surface Area of NaF on the Nucleation of the β-Phase
Czerny J, Heil F, Egbers CJ, Haase M
Chemistry of Materials, (2020) 32 (13), 5691-5699
Heme binding of transmembrane signaling proteins undergoing regulated intramembrane proteolysis
Kupke T, Klare JP, Brügger B
Commun Biol, (2020) Feb 14;3(1):73
Learning algebraic decompositions using Prony structures
Kunis S, Römer T, and von der Ohe U
Adv in Appl Math, (2020) 118, 102044
LiYF\(_{4}\):Yb/LiYF\(_{4}\): and LiYF\(_{4}\)::Yb,Er/LiYF\(_{4}\): core/shell nanocrystals with luminescence decay times similar to YLF laser crystals and the upconversion quantum yield of the Yb,Er doped nanocrystals
Carl F, Birk L, Grauel B, Pons M, Würth C, Resch-Genger U, Haase M
Nano Research, (2020)
A conserved and regulated mechanism drives endosomal Rab transition
Langemeyer L, Borchers AC, Herrmann E, Füllbrunn N, Han Y, Perz A, Auffarth K, Kümmel D, Ungermann C
Elife, (2020) 9:e56090
Time‐Resolved Nonlinear Diffuse fs‐Pulse Reflectometry Using Lithium Niobate Nanoparticles with Two Pulses of Different Colors
Kijatkin C, Bourdon B, Klenen J, Kocsor L, Szaller Z, Imlau M
Adv Photonics Res, (2020) Sep 29
Dual-color 3D-dSTORM colocalization and quantification of ROXY1 and RNAPII variants throughout the transcription cycle in root meristem nuclei
Maß L, Holtmannspötter M, Zachgo S
Plant J, (2020) Sep 8
The role of cations in hydrothermal synthesis of nonlinear optical sodium niobate nanocrystals
Kohlenbach ND, Kijatkin C, König M, Haase M, Imlau M, Kömpe K
Nanoscale, (2020) Sep 15
AP‐3 vesicle uncoating occurs after HOPS‐dependent vacuole tethering
Schoppe J, Mari M, Yavavli E, Auffarth K, Cabrera M, Walter S, Fröhlich F, Ungermann C
EMBO J, (2020) Aug 25:e105117
Next-Generation Surrogate Wnts Support Organoid Growth and Deconvolute Frizzled Pleiotropy In Vivo
Miao Y, Ha A, de Lau W, Yuki K, Santos AJM, You C, Geurts MH, Puschhof J, Pleguezuelos-Manzano C, Peng WC, Senlice R, Piani C, Buikema JW, Gbenedio OM, Vallon M, Yuan J, de Haan S, Hemrika W, Rösch K, Dang LT, Baker D, Ott M, Depeille P, Wu SM, Drost J, Nusse R, Roose JP, Piehler J, Boj SF, Janda CY, Clevers H, Kuo CJ, Garcia KC
Cell Stem Cell, (2020) S1934-5909(20)30358-1
In cellulo protein semi‐synthesis from endogenous and exogenous fragments using the ultra‐fast split Gp41‐1 intein
Bhagawati M, Hoffmann S, Höffgen KS, Piehler J, Busch K, Mootz HD
Angew Chem Int Ed Engl, (2020) Aug 10
In cell Gd\(^{3+}\)-based site-directed spin labeling and EPR spectroscopy of eGFP
Kucher S, Korneev S, Klare JP, Klose D, Steinhoff HJ
Phys Chem Chem Phys, (2020) 22(24):13358-13362
Live imaging of intra-lysosome pH in cell lines and primary neuronal culture using a novel genetically encoded biosensor
Ponsford AH, Ryan TA, Raimondi A, Cocucci E, Wycislo SA, Fröhlich F, Swan LE, Stagi M
Autophagy, (2020) Jun 9:1-19
Lipid dynamics in nanoparticles formed by maleic acid-containing copolymers: EPR spectroscopy and molecular dynamics simulations
Colbasevici A, Voskoboynikova N, Orekhov PS, Bozdaganyan ME, Karlova MG, Sokolova OS, Klare JP, Mulkidjanian AY, Shaitan KV, Steinhoff HJ
Biochim Biophys Acta Biomembr, (2020) 1862(5):183207
Uptake of exogenous serine is important to maintain sphingolipid homeostasis in Saccharomyces cerevisiae
Esch BM, Limar S, Bogdanowski A, Gournas C, More T, Sundag C, Walter S, Heinisch JJ, Ejsing CS, André B, Fröhlich F
PLoS Genet, (2020) 16(8):e1008745
A trimeric metazoan Rab7 GEF complex is crucial for endocytosis and scavenger function
Dehnen L, Janz M, Verma JK, Psathaki OE, Langemeyer L, Fröhlich F, Heinisch JJ, Meyer H, Ungermann C, Paululat A
Journal of Cell Science, (2020) 4133(13):jcs247080
The spatio-temporal organization of mitochondrial F\(_{1}\)F\(_{0}\)ATP synthase in cristae depends on its activity mode
Salewskij K, Rieger B, Hager F, Arroum T, Duwe P, Villalta J, Colgiati S, Richter CP, Psathaki OE, Enriquez JA, Dellmann T, Busch KB
Biochim Biophys Acta Bioenerg, (2020) 1861(1):148091
A trafficome-wide RNAi screen reveals deployment of early and late secretory host proteins and the entire late endo-/lysosomal vesicle fusion machinery by intracellular Salmonella
Kehl A, Göser V, Reuter T, Liss V, Franke M , John C, Richter CP, Deiwick J, Hensel M
PLoS Pathog, (2020) 16(7):e1008220
Novel Fluorescent Mitochondria-Targeted Probe MitoCLox Reports Lipid Peroxidation in Response to Oxidative Stress In Vivo
Lyamzaev KG, Panteleeva AA, Karpukhina AA, Galkin II, Popova EN, Pletjushkina OY, Rieger B, Busch KB, Mulkidjanian AY, Chernyak BV
Oxid Med Cell Longev, (2020) 3631272
Self-assembly of robust gold nanoparticle monolayer architectures for quantitative protein interaction analysis by LSPR spectroscopy
Flesch J, Kappen M, Drees C, You C, Piehler J
Analytical and Bioanalytical Chemistr, (2020) 412:3413–3422
Type I IFN is siloed in endosomes
Altman JB, Taft J, Wedeking T, Gruber CN, Holtmannspötter M, Piehler J, and Bogunovic D,
PNAS, (2020) 30, 17510-17512
Mechanism of homodimeric cytokine receptor activation and dysregulation by oncogenic mutations
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Kinetics of cytokine receptor trafficking determine signaling and functional selectivity
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A randomized multivariate matrix pencil method for superresolution microscopy
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Blocks in Tricarboxylic Acid Cycle of Salmonella enterica Cause Global Perturbation of Carbon Storage, Motility, and Host-Pathogen Interaction
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MitoCLox: A Novel Mitochondria-Targeted Fluorescent Probe for Tracing Lipid Peroxidation
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Nonlinear Optical Potassium Niobate Nanocrystals as Harmonic Markers: The Role of Precursors and Stoichiometry in Hydrothermal Synthesis
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Ligand-induced type II interleukin-4 receptor dimers are sustained by rapid re-association within plasma membrane microcompartments
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Magnetic control of cellular processes using biofunctional nanoparticles
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Engineered Ferritin for Magnetogenetic Manipulation of Proteins and Organelles Inside Living Cells
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Surrogate Wnt agonists that phenocopy canonical Wnt and beta-catenin signalling
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Binding of interferon reduces the force of unfolding for interferon receptor 1
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ER residency of the ceramide phosphoethanolamine synthase SMSr relies on homotypic oligomerization mediated by its SAM domain
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Switching head group selectivity in mammalian sphingolipid biosynthesis by active-site-engineering of sphingomyelin synthases
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Drosophila neprilysins control insulin signaling and food intake via cleavage of regulatory peptides
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Monitoring Changes in the Oligomeric State of a Candidate Endoplasmic Reticulum (ER) Ceramide Sensor by Single-molecule Photobleaching
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Functional protein micropatterning for drug design and discovery
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Receptor dimer stabilization by hierarchical plasma membrane microcompartments regulates cytokine signaling
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Functional interplay between SA1 and TRF1 in telomeric DNA binding and DNA-DNA pairing
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Bioinspired monolithic polymer microsphere arrays as generically anti-adhesive surfaces
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Engineered Upconversion Nanoparticles for Resolving Protein Interactions inside Living Cells
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Single molecule super-resolution imaging of proteins in living Salmonella enterica using self-labelling enzymes
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Structure of the Tuberous Sclerosis Complex 2 (TSC2) N Terminus Provides Insight into Complex Assembly and Tuberous Sclerosis Pathogenesis
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The N-terminus of the floral Arabidopsis TGA transcription factor PERIANTHIA mediates redox-sensitive DNA-binding
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