Main content
Top content
Selected Publications
2022
Biofunctional nanodot arrays in living cells uncover synergistic co-condensation of Wnt signalodroplets
Philippi M, Richter CP, Kappen M, Watrinet I, Miao Y, Runge M, Jorde L, Korneev S, Holtmannspötter M, Kurre R, Holthuis JCM, Garcia KC, Plückthun A, Steinhart M, Piehler J, You C (2022)
Small e2203723.
The ABC transporter MsbA adopts the wide inward-open conformation in E. coli cells
Galazzo L, Meier G, Januliene D, Parey K, De Vecchis D, Striednig B, Hilbi H, Schäfer LV, Kuprov I, Moeller A, Bordignon E, Seeger MA (2022)
Sci Adv. 8(41):eabn6845.
Super-resolution imaging and quantitative analysis of microtubule arrays in model neurons show that epothilone D increases the density but decreases the length and straightness of microtubules in axon-like processes
Conze C, Trushina NI, Holtmannspötter M, Rierola M, Attanasio S, Bakota L, Piehler J, Brandt R (2022)
Brain Res Bull. 190:234-243.
Reactive additive capillary stamping with double network hydrogel-derived aerogel stamps under solvothermal conditions
Alarslan F, Frosinn M, Ruwisch K, Thien J, Jähnichen T, Eckert L, Klein J, Haase M, Enke D, Wollschläger J, Beginn U, Steinhart M (2022)
ACS Appl. Mater. Interfaces 14(39):44992–45004
Pathogenic variants of sphingomyelin synthase SMS2 disrupt lipid landscapes in the secretory pathway
Sokoya T, Parolek J, Foged MM, Danylchuk DI, Bozan M, Sarkar B, Hilderink A, Philippi M, Botto LD, Terhal PA, Mäkitie O, Piehler J, Kim Y, Burd CG, Klymchenko AS, Maeda K, Holthuis JCM. (2022)
Elife. 11:e79278.
Structure of the HOPS tethering complex, a lysosomal membrane fusion machinery
Shvarev D, Schoppe J, König C, Perz A, Füllbrunn N, Kiontke S, Langemeyer L, Januliene D, Schnelle K, Kümmel D, Fröhlich F, Moeller A, Ungermann C. (2022)
Elife 11:e80901. Online ahead of print.
Preparation of drosophila tissues and organs for transmission electron microscopy
Psathaki OE, Paululat A. (2022)
Methods Mol Biol. 2540:361-385.
Proton-gradient-driven sensitivity enhancement of liposome-encapsulated supramolecular chemosensors
Nilam M, Karmacharya S, Nau WM, Hennig A. (2022)
Angew Chem Int Ed Engl. 61(35):e202207950.
Pathogenic autoantibodies to IFN-γ act through the impedance of receptor assembly and Fc-mediated response
Shih HP, Ding JY, Sotolongo Bellón J, Lo YF, Chung PH, Ting HT, Peng JJ, Wu TY, Lin CH, Lo CC, Lin YN, Yeh CF, Chen JB, Wu TS, Liu YM, Kuo CY, Wang SY, Tu KH, Ng CY, Lei WT, Tsai YH, Chen JH, Chuang YT, Huang JY, Rey FA, Chen HK, Chang TW, Piehler J, Chi CY, Ku CL. (2022)
J Exp Med. 219(9):e20212126.
Densely methylated DNA traps Methyl-CpG Binding Domain protein 2 but permits free diffusion by Methyl-CpG Binding Domain protein 3
Leighton GO, Irvin EM, Kaur P, Liu M, You C, Bhattaram D, Piehler J, Riehn R, Wang H, Pan H, Williams DC Jr. (2022)
Biol Chem. 26:102428.
An alliance between lipid transfer proteins and scramblases for membrane expansion
Holthuis JCM, Jahn H, Menon AK, Mizushima N. (2022)
Fac Rev. 11:22
Identification of a thyroid hormone binding site in Hsp90 with implications for its interaction with thyroid hormone receptor beta.
Fan L, Kishore A, Jansen-Olliges L, Wang D, Stahl F, Psathaki OE, Harre J, Warnecke A, Weder J, Preller M, Zeilinger C. (2022)
ACS Omega. 7(33):28932-28945.
Cvm1 is a component of multiple vacuolar contact sites required for sphingolipid homeostasis
Bisinski DD, Gomes Castro I, Mari M, Walter S, Fröhlich F, Schuldiner M, González Montoro A. (2022)
J Cell Biol. 221(8):e202103048.
Neprilysins regulate muscle contraction and heart function via cleavage of SERCA-inhibitory micropeptides
Schiemann R, Buhr A, Cordes E, Walter S, Heinisch JJ, Ferrero P, Milting H, Paululat A, Meyer H (2022)
Nat Commun. 13(1):4420
A Drosophila melanogaster model for TMEM43 related Arrhythmogenic right ventricular cardiomyopathy type 5
Klinke N, Meyer H, Ratnavadivel S, Reinhardt M, Heinisch JJ, Malmendal A, Milting H, Paululat A (2022)
Cell Mol Life Sci. 79(8):444
Organizing structural principles of the interleukin-17 ligand-receptor axis
Wilson SC, Caveney NA, Yen M, Pollmann C, Xiang X, Jude KM, Hafer M, Tsutsumi N, Piehler J, Garcia KC. (2022)
Nature, 609:622–629.
Vesicle transport: Exocyst follows PIP2 to tether membranes
Langemeyer L, Ungermann C. (2022)
Curr Biol. 32(13):R748-R750.
The HOPS tethering complex is required to maintain signaling endosome identity and TORC1 activity
Gao J, Nicastro R, Péli-Gulli M-P, Grziwa S, Chen Z, Kurre R, Piehler J, De Virgilio C, Fröhlich F, Ungermann C (2022)
J Cell Biol 221(5):e202109084.
Dissociation of β2m from MHC class I triggers formation of noncovalent, transient heavy chain dimers
Dirscherl C, Löchte S, Hein Z, Kopicki JD, Harders AR, Linden N, Karner A, Preiner J, Weghuber J, Garcia-Alai M, Uetrecht C, Zacharias M, Piehler J, Lanzerstorfer P, Springer S (2022)
J Cell Sci. jcs.259498
The yeast LYST homolog Bph1 is a Rab5 effector and prevents Atg8 lipidation at endosomes
Vargas Duarte P, Hardenberg R, Mari M, Walter S, Reggiori F, Fröhlich F, González Montoro A, Ungermann C (2022)
J Cell Sci. 135(8):jcs259421
Caspase-cleaved tau is senescence-associated and induces a toxic gain of function by putting a brake on axonal transport
Conze C, Rierola M, Trushina NI, Peters M, Janning D, Holzer M, Heinisch JJ, Arendt T, Bakota L, Brandt R. (2022)
Mol Psychiatry. Online ahead of print.
Intracellular Salmonella Paratyphi A is motile and differs in the expression of flagella-chemotaxis, SPI-1 and carbon utilization pathways in comparison to intracellular S. Typhimurium
Cohen H, Hoede C, Scharte F, Coluzzi C, Cohen E, Shomer I, Mallet L, Holbert S, Serre RF, Schiex T, Virlogeux-Payant I, Grassl GA, Hensel M, Chiapello H, Gal-Mor O (2022)
PLoS Pathog. 18(4):e1010425.
A lysosomal biogenesis map reveals the cargo spectrum of yeast vacuolar protein targeting pathways
Eising S, Esch B, Wälte M, Vargas Duarte P, Walter S, Ungermann C, Bohnert M, Fröhlich F (2022)
J Cell Biol. 221(4):e202107148.
Ca2+-activated sphingomyelin scrambling and turnover mediate ESCRT-independent lysosomal repair
Niekamp P, Scharte F, Sokoya T, Vittadello L, Kim Y, Deng Y, Südhoff E, Hilderink A, Imlau M, Clarke CJ, Hensel M, Burd CG, Holthuis JCM (2022)
Nature Communications 13:1875
Confocal real-time analysis of cutaneous platelet recruitment during immune-complex-mediated inflammation
Currie SM, Stegmeyer RI, Mildner K, Breitsprecher L, Zeuschner D, Psathaki OE, Schäfer K, Wilkens M, Volkery S, Nieswandt B, Vestweber D. (2022) J Invest Dermatol. 31:S0022-202X(22)00254-8.
Low membrane fluidity triggers lipid phase separation and protein segregation in living bacteria
Gohrbandt M, Lipski A, Grimshaw JW, Buttress JA, Baig Z, Herkenhoff B, Walter S, Kurre R, Deckers-Hebestreit G, Strahl H. (2022)
EMBO J. e109800.
Compartmentation and functions of sphingolipids
Körner C, Fröhlich F (2022)
Curr Opin Cell Biol. 74:104-111.
Monitoring and quantification of the dynamics of sress granule components in living cells by fluorescence decay after photoactivation
Söhnel AC, Trushina NI, Brandt R (2022)
Methods Mol Biol. 2428:243-259.
Structure of the Mon1-Ccz1 complex reveals molecular basis of membrane binding for Rab7 activation
Klink B, Herrmann E, Antoni C, Langemeyer L, Kiontke S, Gatsogiannis C, Ungermann C, Raunser S, Kümmel D (2022)
Proc Natl Acad Sci U S A. 119(6):e2121494119.
Bio-inspired adhesion control with liquids
Chen Y, Zhu Z, Steinhart M, Gorb SN. (2022)
iScience. 25(3):103864.
Four-color single-molecule imaging with engineered tags resolves the molecular architecture of signaling complexes in the plasma membrane
Bellón JS, Birkholz O, Richter CP, Eull F, Kenneweg H, Wilmes S, Rothbauer U, You C, Walter MR, Kurre R, Piehler J (2022)
Cell Reports Methods 2(2) 100165
Systematic Assessment of the Accuracy of Subunit Counting in Biomolecular Complexes Using Automated Single-Molecule Brightness Analysis
Danial JSH, Quintana Y, Ros U, Shalaby R, Margheritis EG, Chumpen Ramirez S, Ungermann C, Garcia-Saez AJ, Cosentino K (2022)
J Phys Chem Lett. 13(3):822-829
Frozen motion: how cryo-EM changes the way we look at ABC transporters
Shvarev D, Januliene D, Moeller A (2022)
Trends Biochem Sci. 47(2):136-148.
Surface modification of polycaprolactone scaffold with improved biocompatibility and controlled growth factor release for enhanced stem cell differentiation
Qin X, Wu Y, Liu S, Yang L, Yuan H, Cai S, Flesch J, Li Z, Tang Y, Li X, Zhuang Y, You C, Liu C, Yu C.
(2022)
Front Bioeng Biotechnol. 9:802311.
2021
Cationic ordering and its influence on the magnetic properties of co-rich cobalt ferrite thin films prepared by reactive solid phase epitaxy on Nb-doped SrTiO3(001)
Thien J, Bahlmann J, Alexander A, Ruwisch K, Rodewald J, Pohlmann T, Hoppe M, Alarslan F, Steinhart M, Altuncevahir B, Shafer P, Meyer C, Bertram F, Wollschläger J, Küpper K. (2021)
Materials (Basel). 15(1):46.
NIR-to-NIR imaging: extended excitation up to 2.2 μm using harmonic nanoparticles with a tunable hIGh EneRgy (TIGER) widefield microscope
Vittadello L, Klenen J, Koempe K, Kocsor L, Szaller Z, Imlau M (2021)
Nanomaterials (Basel). 11(12):3193.
Ischemic tolerance and cardiac repair in the spiny mouse (Acomys)
Koopmans T, van Beijnum H, Roovers EF, Tomasso A, Malhotra D, Boeter J, Psathaki OE, Versteeg D, van Rooij E, Bartscherer K (2021)
NPJ Regen Med. 6(1):78.
Phenolic resin dual-use stamps for capillary stamping and decal transfer printing
Guo L, Klein J, Thien J, Philippi M, Haase M, Wollschläger J, Steinhart M. (2021)
ACS Appl Mater Interfaces. 2021 13(41):49567-49579.
Single cell analyses reveal distinct adaptation of typhoidal and non-typhoidal Salmonella enterica serovars to intracellular lifestyle
Röder J, Felgner P, Hensel M. (2021)
Cell Microbiol. 23(10):e13374.
Micro-Meta App: an interactive tool for collecting microscopy metadata based on community specifications
Rigano A, Ehmsen S, Öztürk SU, Ryan J, Balashov A, Hammer M, Kirli K, Boehm U, Brown CM, Bellve K, Chambers JJ, Cosolo A, Coleman RA, Faklaris O, Fogarty KE, Guilbert T, Hamacher AB, Itano MS, Keeley DP, Kunis S, Lacoste J, Laude A, Ma WY, Marcello M, Montero-Llopis P, Nelson G, Nitschke R, Pimentel JA, Weidtkamp-Peters S, Park PJ, Alver BH, Grunwald D, & Strambio-De-Castillia C (2021)
Nat Methods. 18(12):1489-1495
Subunit exchange among endolysosomal tethering complexes is linked to contact site formation at the vacuole
Gonzáles Montoro A, Vargas Duarte P, Auffarth K, Walter S, Fröhlich F, & Ungermann C (2021)
Mol Biol Cell. 32(22):br14.
IFNAR1 and IFNAR2 play distinct roles in initiating type I interferon-induced JAK-STAT signaling and activating STATs
Shemesh M, Lochte S, Piehler J, & Schreiber G
Sci Signal (2021) Nov 23;14(710):eabe4627
Subunit exchange among endolysosomal tethering complexes is linked to contact site formation at the vacuole
González Montoro A, Duarte PV, Auffarth K, Walter S, Fröhlich F, Ungermann C
Mol Biol Cell (2021) Nov 18 32(22) mbc.E21-05-0227
Metabolic dissimilarity determines the establishment of cross-feeding interactions in bacteria
Giri S, Oña L, Waschina S, Shitut S, Yousif G, Kaleta C, Kost C
Curr Biol. (2021) Oct 27;S0960-9822(21)01408-1
Dendrite tapering actuates a self-organizing signaling circuit for stochastic filopodia initiation in neurons
Mancinelli G, Lamparter L, Nosov G, Saha T, Pawluchin A, Kurre R, Rasch C, Ebrahimkutty M, Klingauf J, & Galic M
Proc Natl Acad Sci U S A (2021) Oct 26;118(43):e2106921118
Flexible open conformation of the AP-3 complex explains its role in cargo recruitment at the Golgi
Schoppe J, Schubert E, Apelbaum A, Yavavli E, Birkholz O, Stephanowitz H, Han Y, Perz A, Hofnagel O, Liu F, Piehler J, Raunser S, Ungermann C
J Biol Chem. (2021) 101334
A reference scale of cucurbit[7]uril binding affinities
Alnajja MA, Nau WM, & Hennig A
Org Biomol Chem (2021) Oct 14;19(39):8521-8529
Diffraction-Unlimited Photomanipulation at the Plasma Membrane via Specifically Targeted Upconversion Nanoparticles
Drees C, Rühl P, Czerny J, Chandra G, Bajorath J, Haase M, Heinemann SH, Piehler J
Nano Lett. (2021) Oct 13;21(19):8025-8034.
MDEmic: a metadata annotation tool to facilitate management of FAIR image data in the bioimaging community
Kunis S, Hänsch S, Schmidt C, Wong F, Strambio-De-Castillia C, Weidtkamp-Peters S
Nature Methods (2021) Oct 11 doi.org/10.1038/s41592-021-01288-z
QUAREP-LiMi: A community-driven initiative to establish guidelines for quality assessment and reproducibility for instruments and images in light microscopy
Nelson G, Boehm U, Bagley S, Bajcsy P, Bischof J, Brown CM, Dauphin A, Dobbie IM, Eriksson JE, Faklaris O, Fernandez-Rodriguez J, Ferrand A, Gelman L, Gheisari A, Hartmann H, Kukat C, Laude A, Mitkovski M, Munck S, North AJ, Rasse TM, Resch-Genger U, Schuetz LC, Seitz A, Strambio-De-Castillia C, Swedlow JR, Alexopoulos I, Aumayr K, Avilov S, Bakker G-J, Bammann RR, Bassi A, Beckert H, Beer S, Belyaev Y, Bierwagen J, Birngruber KA, Bosch M, Breitlow J, Cameron LA, Chalfoun J, Chambers JJ, Chen C-L, Conde-Sousa E, Corbett AD, Cordelieres FP, Del Nery E, Dietzel R, Eismann F, Fazeli E, Felscher A, Fried H, Gaudreault N, Goh WI , Guilbert T, Hadleigh R, Hemmerich P, Holst GA, Itano MS, Jaffe CB, Jambor HK, Jarvis SC, Keppler A, Kirchenbuechler D, Kirchner M, Kobayashi N, Krens G, Kunis S, Lacoste J, Marcello M, Martins GG, Metcalf DJ, Mitchell CA, Moore J, Mueller T, Nelson MS, Ogg S, Onami S, Palmer AL, Paul-Gilloteaux P, Pimentel JA, Plantard L, Podder S, Rexhepaj E, Royon A, Saari MA, Schapman D, Schoonderwoert V, Schroth-Diez B, Schwartz S, Shaw M, Spitaler M, Stoeckl MT, Sudar D, Teillon J, Terjung S, Thuenauer R, Wilms CD, Wright GD, & Nitschke R
J Microsc (2021) Oct;284(1):56-73.
Flexible open conformation of the AP-3 complex explains its role in cargo recruitment at the Golgi
Schoppe J, Schubert E, Apelbaum A, Yavavli E, Birkholz O, Stephanowitz H, Han Y, Perz A, Hofnagel O, Liu F, Piehler J, Raunser S, & Ungermann C
J Biol Chem 297 (2021), 101334
The small GTPase KlRho5 responds to oxidative stress and affects cytokinesis
Musielak M, Sterk CC, Schubert F, Meyer C, Paululat A, Heinisch JJ
J Cell Sci. (2021), Sep 15;134(18):jcs258301
Obligate cross-feeding expands the metabolic niche of bacteria
Oña L, Giri G, Avermann N, Kreienbaum M, Thormann KM, Kost C
Nat Ecol Evol. (2021) Sep;5(9):1224-1232
TSC1 binding to lysosomal PIPs is required for TSC complex translocation and mTORC1 regulation
Fitzian K, Brückner A, Brohée L, Zech R, Antoni C, Kiontke S, Gasper R, Linard Matos AL, Beel S, Wilhelm S, Gerke V, Ungermann C, Nellist M, Raunser S, Demetriades C, Oeckinghaus A, & Kümmel D
Mol Cell (2021), Jul 1 81(13):2705-2721
Who’s in control? Principles of Rab GTPase activation in endolysosomal membrane trafficking and beyond
Borchers AC, Langemeyer L, & Ungermann C
J Cell Biol (2021) 220 (9): e202105120
Apoptosis-inducing anti-HER2 agents operate through oligomerization-induced receptor immobilization
Stüber JC, Richter CP, Sotolongo Bellón J, Schwill M, König I, Schuler B, Piehler J, Plückthun A
Commun Biol, (2021) Jun 21;4(1):762
In-vivo tracking of harmonic nanoparticles: a study based on a TIGER widefield microscope
Vittadello L, Kijatkin C, Klenen J, Dzikonski D, Kömpe K, Meyer C, Paululat A, Imlau M
Optical Materials Express, (2021) 11, 1953-1969
Engineering an anti-HER2 biparatopic antibody with a multimodal mechanism of action
Kast F, Schwill M, Stüber JC, Pfundstein S, Nagy-Davidescu G, Rodríguez JMM, Seehusen F, Richter CP, Honegger A, Hartmann KP, Weber TG, Kroener F, Ernst P, Piehler J, Plückthun A
Nat Commun, (2021) Jun 18;12(1):3790
Evaluation of DIBMA nanoparticles of variable size and anionic lipid content as tools for the structural and functional study of membrane proteins
Voskoboynikova N, Margheritis EG, Kodde F, Rademacher M, Schowe M, Budke-Gieseking A, Psathaki OE, Steinhoff HJ, Cosentino K
Biochim Biophys Acta Biomembr, (2021) Jun 1;1863(6):183588
TSC1 binding to lysosomal PIPs is required for TSC complex translocation and mTORC1 regulation
Fitzian K, Brückner A, Brohée L, Zech R, Antoni C, Kiontke S, Gasper R, Linard Matos AL, Beel S, Wilhelm S, Gerke V, Ungermann C, Nellist M, Raunser S, Demetriades C, Oeckinghaus A, Kümmel D
Mol Cell, (2021) Apr 30:S1097-2765(21)00324-5
Lipid Dynamics in Diisobutylene-Maleic Acid (DIBMA) Lipid Particles in Presence of Sensory Rhodopsin II
Voskoboynikova N, Orekhov P, Bozdaganyan M, Kodde F, Rademacher M, Schowe M, Budke-Gieseking A, Brickwedde B, Psathaki OE, Mulkidjanian AY, Cosentino K, Shaitan KV, Steinhoff HJ
Int J Mol Sci, (2021) Mar 4;22(5):2548
The protected physiological state of intracellular Salmonella enterica persisters reduces host cell-imposed stress
Schulte M, Olschewski K, Hensel M
Commun Biol, (2021) May 4;4(1):520
Calibration of cell-intrinsic interleukin-2 response thresholds guides design of a regulatory T cell biased agonist
Glassman CR, Su L, Majri-Morrison SS, Winkelmann H, Mo F, Li P, Pérez-Cruz M, Ho PP, Koliesnik I, Nagy N, Hnizdilova T, Picton LK, Kovar M, Bollyky P, Steinman L, Meyer E, Piehler J, Leonard WJ, Garcia KC
Elife, (2021) May 18;10:e65777
Biofunctionalization of carbon nanotubes for reversible site-specific protein immobilization
Jorde L, Li Z, Pöppelwerth A, Piehler J, You C, Meyer C
Journal of Applied Physics, (2021) 129, 094302
Competitive binding of STATs to receptor phospho-Tyr motifs accounts for altered cytokine responses
Wilmes S, Jeffrey PA, Martinez-Fabregas J, Hafer M, Fyfe PK, Pohler E, Gaggero S, López-García M, Lythe G, Taylor C, Guerrier T, Launay D, Mitra S, Piehler J, Molina-París C, Moraga I
Elife, (2021) Apr 19;10:e66014
TSC1 binding to lysosomal PIPs is required for TSC complex translocation and mTORC1 regulation
Fitzian K, Brückner A, Brohée L, Zech R, Antoni C, Kiontke S, Gasper R, Linard Matos AL, Beel S, Wilhelm S, Gerke V, Ungermann C, Nellist M, Raunser S, Demetriades C, Oeckinghaus A, Kümmel D
Mol Cell, (2021) Apr 30:S1097-2765(21)00324-5
Fluorescent protein-based reporters reveal stress response of intracellular Salmonella enterica at level of single bacterial cells
Schulte M, Olschewski K, Hensel M
Cell Microbiol, (2021) Mar;23(3):e13293
n-type Ge/Si antennas for THz sensing
Chavarin CA, Hardt E, Gruessing S, Skibitzki O, Costina I, Spirito D, Seifert W, Klesse W, Manganelli CL, You C, Flesch J, Piehler J, Missori M, Baldassarre L, Witzigmann B, Capellini G
Opt Express, (2021) Mar 1;29(5):7680-7689
Correlative Light and Scanning Electron Microscopy to Study Interactions of Salmonella enterica with Polarized Epithelial Cell Monolayers
Kommnick C, Hensel M
Methods Mol Biol, (2021) J2182:103-115
Three-Dimensional Interfacing of Cells with Hierarchical Silicon Nano/Microstructures for Midinfrared Interrogation of In Situ Captured Proteins
Flesch J, Bettenhausen M, Kazmierczak M, Klesse WM, Skibitzki O, Psathaki OE, Kurre R, Capellini G, Guha S, Schroeder T, Witzigmann B, You C, Piehler J
ACS Appl Mater Interfaces, (2021) Feb 11
Self-Labeling Enzyme Tags for Translocation Analyses of Salmonella Effector Proteins
Göser V, Hensel M
Methods Mol Biol, (2021) 2182:67-82
Short Photoswitchable Ceramides Enable Optical Control of Apoptosis
Morstein J, Kol M, Novak AJE, Feng S, Khayyo S, Hinnah K, Li-Purcell N, Pan G, Williams BM, Riezman H, Atilla-Gokcumen GE, Holthuis JCM, Trauner D
ACS Chem Biol, (2021) Mar 19;16(3):452-456
A Three-Dimensional Model of the Yeast Transmembrane Sensor Wsc1 Obtained by SMA-Based Detergent-Free Purification and Transmission Electron Microscopy
Voskoboynikova N, Karlova M, Kurre R, Mulkidjanian AY, Shaitan KV, Sokolova OS, Steinhoff HJ, Heinisch JJ
J Fungi (Basel), (2021) Feb 5;7(2):118
Zn\(^{2+}\) Intoxication of Mycobacterium marinum during Dictyostelium discoideum Infection Is Counteracted by Induction of the Pathogen Zn\(^{2+}\) Exporter CtpC
Hanna N, Koliwer-Brandl H, Lefrançois LH, Kalinina V, Cardenal-Muñoz E, Appiah J, Leuba F, Gueho A, Hilbi H, Soldati T, Barisch C
mBio, (2021) Feb 2;12(1):e01313-20
Nanoscopic anatomy of dynamic multi-protein complexes at membranes resolved by graphene-induced energy transfer
Füllbrunn N, Li Z, Jorde L, Richter CP, Kurre R, Langemeyer L, Yu C, Meyer C, Enderlein J, Ungermann C, Piehler J, You C
Elife, (2021) Jan 29;10:e62501
Sphingomyelin Biosynthesis Is Essential for Phagocytic Signaling during Mycobacterium tuberculosis Host Cell Entry
Niekamp P, Guzman G, Leier HC, Rashidfarrokhi A, Richina V, Pott F, Barisch C, Holthuis JCM, Tafesse FG
mBio, (2021) Jan 26;12(1):e03141-20
TORC1 Determines Fab1 Lipid Kinase Function at Signaling Endosomes and Vacuoles
Chen Z, Malia PC, Hatakeyama R, Nicastro R, Hu Z, Péli-Gulli MP, Gao J, Nishimura T, Eskes E, Stefan CJ, Winderickx J, Dengjel J, De Virgilio C, Ungermann C
Curr Biol,(2021) Jan 25;31(2):297-309.e8
Membrane Permeability and Its Activation Energies in Dependence on Analyte, Lipid, and Phase Type Obtained by the Fluorescent Artificial Receptor Membrane Assay
Nilan M, Collin S, Karmacharya S. Hennig A, & Nau WM
ACS Sens (2021) Jan 22;6(1):175-182
Tuning MPL signaling to influence hematopoietic stem cell differentiation and inhibit essential thrombocythemia progenitors
Cui L, Moraga I, Lerbs T, Van Neste C, Wilmes S, Tsutsumi N, Trotman-Grant AC, Gakovic M, Andrews S, Gotlib J, Darmanis S, Enge M, Quake S, Hitchcock IS, Piehler J, Garcia KC, Wernig G
Proc Natl Acad Sci USA, (2021) Jan 12;118(2):e2017849118 (2021)
Capillary Stamping of Functional Materials: Parallel Additive Substrate Patterning without Ink Depletion
Runge M, Hübner H, Grimm A, Manoharan G, Wieczorek R, Philippi M, Harneit W, Meyer C, Enke D, Gallei M, Steinhart M
Advanced Materials Interfaces, (2021) 8, 2001911
2020
Interaction of Cucurbit[7]uril with protease substrates: application to nanosecond time-resolved fluorescence assays
Hennig A, Nau WM
Front Chem (2020) Sep 10
Parallelized Manipulation of Adherent Living Cells by Magnetic Nanoparticles-Mediated Forces
Bongaerts M, Aizel K, Secret E, Jan A, Nahar T, Raudzus F, Neumann S, Telling N, Heumann R, Siaugue JM, Menager C, Fresnais J, Villard C, El Haj A, Piehler J, Gates MA, & Coppey M
International journal of molecular sciences, 21 (2020)
Na1.5-x/2Gd1.5-x/2SrxF6 nanocrystals: Growth, size control and shell formation on β-NaCeF\(_{4}\):Tb core particles
Wehmeier J, Haase M
CrystEngComm, (2020) 22, 8036-8044
Engineered IL-10 variants elicit potent immunomodulatory effects at low ligand doses
Gorby C, Sotolongo Bellon J, Wilmes S, Warda W, Pohler E, Fyfe PK, Cozzani A, Ferrand C, Walter MR, Mitra S, Piehler J, & Moraga I
Sci Signal, 13, 649 (2020)
Towards a mathematical model for single molecule structured illumination microscopy
Hockmann M, Kunis S, and Kurre R
Proc Appl Math Mech, (2020)
Function of the SNARE Ykt6 on autophagosomes requires the Dsl1 complex and the Atg1 kinase complex
Gao J, Kurre R, Rose J, Walter S, Fröhlich F, Piehler J, Reggiori F, Ungermann C
EMBO Rep, (2020) Oct 7:e50733
Magnetic and Electronic Properties of Highly Mn-Doped β-NaGdF\(_{4}\) and β-NaEuF\(_{4}\) Nanoparticles with a Narrow Size Distribution
Schneider L, Wehmeier J, Wiedwald U, Rodewald J, Galakhov VR, Udintseva MS, Mesilov V, Radu F, Luo C, Klare JP, Steinhoff H-J, Haase M, Kuepper K
J Phys Chem C, (2020) 124, 33, 18194–18202
On the condition number of Vandermonde matrices with pairs of nearly-colliding nodes
Kunis S and Nagel D
Numer Algorithms, (2020)
On the smallest singular value of multivariate Vandermonde matrices with clustered nodes
Kunis S and Nagel D
Linear Algebra Appl, (2020) 604, 1-20
Size-Controlled Growth of β-NaGdF4 and β-NaGdF\(_{4}\):Yb,Er Nanocrystals: The Influence of the Surface Area of NaF on the Nucleation of the β-Phase
Czerny J, Heil F, Egbers CJ, Haase M
Chemistry of Materials, (2020) 32 (13), 5691-5699
Heme binding of transmembrane signaling proteins undergoing regulated intramembrane proteolysis
Kupke T, Klare JP, Brügger B
Commun Biol, (2020) Feb 14;3(1):73
Learning algebraic decompositions using Prony structures
Kunis S, Römer T, and von der Ohe U
Adv in Appl Math, (2020) 118, 102044
LiYF\(_{4}\):Yb/LiYF\(_{4}\): and LiYF\(_{4}\)::Yb,Er/LiYF\(_{4}\): core/shell nanocrystals with luminescence decay times similar to YLF laser crystals and the upconversion quantum yield of the Yb,Er doped nanocrystals
Carl F, Birk L, Grauel B, Pons M, Würth C, Resch-Genger U, Haase M
Nano Research, (2020)
A conserved and regulated mechanism drives endosomal Rab transition
Langemeyer L, Borchers AC, Herrmann E, Füllbrunn N, Han Y, Perz A, Auffarth K, Kümmel D, Ungermann C
Elife, (2020) 9:e56090
Time‐Resolved Nonlinear Diffuse fs‐Pulse Reflectometry Using Lithium Niobate Nanoparticles with Two Pulses of Different Colors
Kijatkin C, Bourdon B, Klenen J, Kocsor L, Szaller Z, Imlau M
Adv Photonics Res, (2020) Sep 29
Dual-color 3D-dSTORM colocalization and quantification of ROXY1 and RNAPII variants throughout the transcription cycle in root meristem nuclei
Maß L, Holtmannspötter M, Zachgo S
Plant J, (2020) Sep 8
The role of cations in hydrothermal synthesis of nonlinear optical sodium niobate nanocrystals
Kohlenbach ND, Kijatkin C, König M, Haase M, Imlau M, Kömpe K
Nanoscale, (2020) Sep 15
AP‐3 vesicle uncoating occurs after HOPS‐dependent vacuole tethering
Schoppe J, Mari M, Yavavli E, Auffarth K, Cabrera M, Walter S, Fröhlich F, Ungermann C
EMBO J, (2020) Aug 25:e105117
Next-Generation Surrogate Wnts Support Organoid Growth and Deconvolute Frizzled Pleiotropy In Vivo
Miao Y, Ha A, de Lau W, Yuki K, Santos AJM, You C, Geurts MH, Puschhof J, Pleguezuelos-Manzano C, Peng WC, Senlice R, Piani C, Buikema JW, Gbenedio OM, Vallon M, Yuan J, de Haan S, Hemrika W, Rösch K, Dang LT, Baker D, Ott M, Depeille P, Wu SM, Drost J, Nusse R, Roose JP, Piehler J, Boj SF, Janda CY, Clevers H, Kuo CJ, Garcia KC
Cell Stem Cell, (2020) S1934-5909(20)30358-1
In cellulo protein semi‐synthesis from endogenous and exogenous fragments using the ultra‐fast split Gp41‐1 intein
Bhagawati M, Hoffmann S, Höffgen KS, Piehler J, Busch K, Mootz HD
Angew Chem Int Ed Engl, (2020) Aug 10
In cell Gd\(^{3+}\)-based site-directed spin labeling and EPR spectroscopy of eGFP
Kucher S, Korneev S, Klare JP, Klose D, Steinhoff HJ
Phys Chem Chem Phys, (2020) 22(24):13358-13362
Live imaging of intra-lysosome pH in cell lines and primary neuronal culture using a novel genetically encoded biosensor
Ponsford AH, Ryan TA, Raimondi A, Cocucci E, Wycislo SA, Fröhlich F, Swan LE, Stagi M
Autophagy, (2020) Jun 9:1-19
Lipid dynamics in nanoparticles formed by maleic acid-containing copolymers: EPR spectroscopy and molecular dynamics simulations
Colbasevici A, Voskoboynikova N, Orekhov PS, Bozdaganyan ME, Karlova MG, Sokolova OS, Klare JP, Mulkidjanian AY, Shaitan KV, Steinhoff HJ
Biochim Biophys Acta Biomembr, (2020) 1862(5):183207
Uptake of exogenous serine is important to maintain sphingolipid homeostasis in Saccharomyces cerevisiae
Esch BM, Limar S, Bogdanowski A, Gournas C, More T, Sundag C, Walter S, Heinisch JJ, Ejsing CS, André B, Fröhlich F
PLoS Genet, (2020) 16(8):e1008745
A trimeric metazoan Rab7 GEF complex is crucial for endocytosis and scavenger function
Dehnen L, Janz M, Verma JK, Psathaki OE, Langemeyer L, Fröhlich F, Heinisch JJ, Meyer H, Ungermann C, Paululat A
Journal of Cell Science, (2020) 4133(13):jcs247080
The spatio-temporal organization of mitochondrial F\(_{1}\)F\(_{0}\)ATP synthase in cristae depends on its activity mode
Salewskij K, Rieger B, Hager F, Arroum T, Duwe P, Villalta J, Colgiati S, Richter CP, Psathaki OE, Enriquez JA, Dellmann T, Busch KB
Biochim Biophys Acta Bioenerg, (2020) 1861(1):148091
A trafficome-wide RNAi screen reveals deployment of early and late secretory host proteins and the entire late endo-/lysosomal vesicle fusion machinery by intracellular Salmonella
Kehl A, Göser V, Reuter T, Liss V, Franke M , John C, Richter CP, Deiwick J, Hensel M
PLoS Pathog, (2020) 16(7):e1008220
Novel Fluorescent Mitochondria-Targeted Probe MitoCLox Reports Lipid Peroxidation in Response to Oxidative Stress In Vivo
Lyamzaev KG, Panteleeva AA, Karpukhina AA, Galkin II, Popova EN, Pletjushkina OY, Rieger B, Busch KB, Mulkidjanian AY, Chernyak BV
Oxid Med Cell Longev, (2020) 3631272
Self-assembly of robust gold nanoparticle monolayer architectures for quantitative protein interaction analysis by LSPR spectroscopy
Flesch J, Kappen M, Drees C, You C, Piehler J
Analytical and Bioanalytical Chemistr, (2020) 412:3413–3422
Type I IFN is siloed in endosomes
Altman JB, Taft J, Wedeking T, Gruber CN, Holtmannspötter M, Piehler J, and Bogunovic D,
PNAS, (2020) 30, 17510-17512
Mechanism of homodimeric cytokine receptor activation and dysregulation by oncogenic mutations
Wilmes S, Hafer M, Vuorio J, Tucker JA, Winkelmann H, Löchte S, Stanly TA, Pulgar Prieto KD , Poojari C, Sharma V, Richter CP, Kurre R, Hubbard SR, Garcia KC, Moraga I, Vattulainen I, Hitchcock IS, Piehler J
Science, 367(6478), 643-652 (2020)
2019
Kinetics of cytokine receptor trafficking determine signaling and functional selectivity
Martinez-Fabregas J, Wilmes S, Wang L, Hafer M, Pohler E, Lokau J, Garbers C, Cozzani A, Fyfe PK, Piehler J, Kazemian M, Mitra S, Moraga I
Elife, (2019) Nov 27;8:e49314
Prony's method on the sphere
Kunis S, Möller HM, and von der Ohe U
SMAI J Comput Math, (2019) 5S, 87-97
Structure of the IFNγ receptor complex guides design of biased agonists
Mendoza JL, Escalante NK, Jude KM, Sotolongo Bellon J, Su L, Horton TM, Tsutsumi N, Berardinelli SJ, Haltiwanger RS, Piehler J, Engleman EG, Garcia KC
Nature, (2019) Mar;567(7746):56-60
A randomized multivariate matrix pencil method for superresolution microscopy
Ehler M, Kunis S, Peter T, and Richter C
Electron Trans Numer Anal, (2019) . 51, 63-74
MpTCP1 controls cell proliferation and redox processes in Marchantia polymorpha
Busch A, Deckena M, Almeida-Trapp M, Kopischke S, Kock C, Schüssler E, Tsiantis M, Mithöfer A, Zachgo S
New Phytol, (2019) Dec;224(4):1627-1641
Close-packed silane nanodot arrays by capillary nanostamping coupled with heterocyclic silane ring opening
Philippi M, You C, Richter CP, Schmidt M, Thien J, Liße D, Wollschlager J, Piehler J and Steinhart M
RSC Adv, 2019, 9, 24742
Blocks in Tricarboxylic Acid Cycle of Salmonella enterica Cause Global Perturbation of Carbon Storage, Motility, and Host-Pathogen Interaction
Noster J, Hansmeier N, Persicke M, Chao TC, Kurre R, Popp J, Liss V, Reuter T, Hensel M
mSphere, (2019) 4(6):e00796-19
Topological control of cytokine receptor signaling induces differential effects in hematopoiesis
Mohan K, Ueda G, Kim AR, Jude KM, Fallas JA, Guo Y, Hafer M, Miao Y, Saxton RA, Piehler J, Sankaran VG, Baker D, Garcia KC
Science, (2019) May 24;364(6442):eaav7532
MitoCLox: A Novel Mitochondria-Targeted Fluorescent Probe for Tracing Lipid Peroxidation
Konstantin G, Lyamzaev KG, Sumbatyan NV, Nesterenko AM, Kholina EG, Voskoboynikova N, Steinhoff H-J, Mulkidjanian AY
Oxid Med Cell Longev, (2019) 9710208
ESEEM Reveals Bound Substrate Histidine in the ABC Transporter HisQMP\(_2\)
Isaev N, Heuveling J, Ivanisenko N, Schneider E, Steinhoff HJ
Applied Magnetic Resonance, 1-11 (2019)
Conformational dynamics of sensory rhodopsin II in nanolipoprotein and styrene-maleic acid lipid particles
Mosslehy W, Voskoboynikova N, Colbasevici A, Ricke A, Klose D, Klare JP, Mulkidzhanyan AY, Steinhoff HJ
Photochem Photobiol, (2019)
Proton leakage across lipid bilayers: Oxygen atoms of phospholipid ester linkers align water molecules into transmembrane water wires
Bozdaganyan ME, Lokhmatikov AV, Voskoboynikova N, Cherepanov DA, Steinhoff HJ, Shaitan KV, Mulkidjanian AY
BBA-Bioenergetics 1860(6), 439-451 (2019)
Styrene/Maleic Acid Copolymers Form SMALPs by Pulling Lipid Patches out of the Lipid Bilayer
Orekhov PS, Bozdaganyan ME, Voskoboynikova N, Mulkidjanian AY, Steinhoff HJ, Shaitan KV
Langmuir 35(10), 3748-3758 (2019)
Detergent-free solubilization of human Kv channels expressed in mammalian cells
Karlova MG, Voskoboynikova N, Gluhov GS, Abramochkin D, Malak OA, Mulkidzhanyan A, Loussouarn G, Steinhoff HJ, Shaitan KV, Sokolova OS
Chem Phys Lipids 219 (2019)
Optical manipulation of sphingolipid biosynthesis using photoswitchable ceramides
Kol M, Williams B, Toombs-Ruane H, Franquelim HG, Korneev S, Schroeer C, Schwille P, Trauner D, Holthuis JC, Frank JA
Elife, 8:e43230 (2019)
Osteoporosis and skeletal dysplasia caused by pathogenic variants in SGMS2
Pekkinen M, Terhal PA, Botto LD, Henning P, Mäkitie RE, Roschger P, Jain A, Kol M, Kjellberg MA, Paschalis EP, van Gassen K, Murray M, Bayrak-Toydemir P, Magnusson MK, Jans J, Kausar M, Carey JC, Somerharju P, Lerner UH, Olkkonen VM, Klaushofer K, Holthuis JC, Mäkitie O
JCI Insight, 4(7):e126180 (2019)
Ceramides bind VDAC2 to trigger mitochondrial apoptosis
Dadsena S, Bockelmann S, Mina JGM, Hassan DG, Korneev S, Razzera G, Jahn H, Niekamp P, Müller D, Schneider M, Tafesse FG, Marrink SJ, Melo MN, Holthuis JCM
Nat Commun, 10(1), 1832 (2019)
A systematic approach to identify recycling endocytic cargo depending on the GARP complex
Eising S, Thiele L, Fröhlich F
eLife 8:e42837 (2019)
2018
Annexins A2 and A6 interact with the extreme N terminus of tau and thereby contribute to tau's axonal localization
Gauthier-Kemper A, Suárez Alonso M, Sündermann F, Niewidok B, Fernandez MP, Bakota L, Heinisch JJ, Brandt R
J Biol Chem, (2018) May 25;293(21):8065-8076
Identification and In Vivo Characterisation of Cardioactive Peptides in Drosophila melanogaster
Schiemann R, Lammers K, Janz M, Lohmann J, Paululat A, Meyer H
Int J Mol Sci., (2018) Dec 20;20(1):2
SERCA is critical to control the Bowditch effect in the heart
Balcazar D, Regge V, Santalla M, Meyer H, Paululat A, Mattiazzi A, Ferrero P
Sci Rep, (2018) 8, 12447
APC/C\(^{Fzr}\) regulates cardiac and myoblast cell numbers, and plays a crucial role during myoblast fusion
Drechsler M, Meyer H, Wilmes AC, Paululat A
J Cell Sci, (2018) Jul 17;131(14):jcs209155
Drosophila pericardial nephrocyte ultrastructure changes during ageing
Psathaki OE, Dehnen L, Hartley PS, Paululat A
Mech Ageing Dev, (2018) 173:9-20
Multi-color Localization Microscopy of Single Membrane Proteins in Organelles of Live Mammalian Cells
Appelhans T, Beinlich FRM, Richter CP, Kurre R, Busch KB
J Vis Exp., (2018) 136:57690
Single-molecule imaging reveals dynamic biphasic partition of RNA-binding proteins in stress granules
Niewidok B, Igaev M, Pereira da Graca A, Strassner A, Lenzen C, Richter CP, Piehler J, Kurre R, Brandt R
J Cell Biol, 217, 1303-1318 (2018)
Stable and selective self-assembly of α-lipoic acid on Ge(001) for biomolecule immobilization
Kazmierczak M, Flesch J, Mitzloff J, Capellini G, Klesse WM, Skibitzki O, You C, Bettenhausen M, Witzigmann B, Piehler J, Schroeder T, Guha S
Journal of Applied Physics, 123, 175305 (2018)
Non-specific interactions govern cytosolic diffusion of nanosized objects in mammalian cells
Etoc F, Balloul E, Vicario C, Normanno D, Liße D, Sittner A, Piehler J, Dahan M, Coppey M
Nature materials, 17, 740-746 (2018)
How nanoscale protein interactions determine the mesoscale dynamic organisation of bacterial outer membrane proteins
Chavent M, Duncan AL, Rassam P, Birkholz O, Hélie J, Reddy T, Beliaev D, Hambly B, Piehler J, Kleanthous C, Sansom MSP
Nat Commun, 9, 2846 (2018)
Multi-functional DNA nanostructures that puncture and remodel lipid membranes into hybrid materials
Birkholz O, Burns JR, Richter CP, Psathaki OE, Howorka S, Piehler J
Nat Commun, 9, 1521 (2018)
Germanium Plasmon Enhanced Resonators for Label-Free Terahertz Protein Sensing
Bettenhausen M, Römer F, Witzigmann B, Flesch J, Kurre R, Korneev S, Piehler J, You C, Kazmierczak M, Guha S, Capellini G, Schröder T
Frequenz, 72, 113-122 (2018)
Near-native, site-specific and purification-free protein labeling for quantitative protein interaction analysis by MicroScale Thermophoresis
Bartoschik T, Galinec S, Kleusch C, Walkiewicz K, Breitsprecher D, Weigert S, Muller YA, You C, Piehler J, Vercruysse T, Daelemans D, Tschammer N
Scientific reports, 8, 4977 (2018)
A search for ceramide binding proteins using bifunctional lipid analogues yields CERT-related protein StarD7
Bockelmann S, Mina JGM, Korneev S, Hassan DG, Müller D, Hilderink A, Vlieg HC, Raijmakers R, Heck AJR, Haberkant P, and Holthuis JC
J Lipid Res,, 59, 515-530 (2018)
Defective cortex glia plasma membrane structure underlies light-induced epilepsy in cpes mutants
Kunduri G, Turner-Evans D, Konya Y, Izumi Y, Nagashima K, Lockett S, Holthuis J, Bamba T, Acharya U, Acharya JK
Proc Natl Acad Sci USA, 115, E8919-E8928 (2018)
Colloidal Crystals of NaYF4 Upconversion Nanocrystals Studied by Small-Angle X-Ray Scattering (SAXS)
Homann C, Bolze J, Haase M
Part Part Syst Charact, 1800391 (2018)
Colloidal LaPO4:Gd\(^{3+}\) nanocrystals: X-ray induced single line UV emission
Espinoza S, Juestel T, Haase M
Nanoscale 10, 22533-22540 (2018)
Deep Ultraviolet Emitting Scintillators for Biomedical Applications: The Hard Way of Downsizing LuPO4:Pr\(^{3+}\)
Espinoza S, Volhard MF, Kätker H, Jenneboer H, Uckelmann A, Haase M, Müller M , Purschke M, Jüstel T
Part Part Syst Charact, 1800282 (2018)
NaYF4:Yb,Er/NaYF4 core/shell nanocrystals with high upconversion luminescence quantum yield
Homann C, Krukewitt L, Frenzel F, Grauel B, Würth C , Resch-Genger U, Haase M
Angew Chem Int Ed, 57, 8765–8769 (2018), DOI
Angew Chem, 130, 8901–8905 (2018), DOI
Holographic performance of silicon polymer films based on photoswitchable molecules
Bourdon B, Bock S, Kijatkin C, Shumelyuk A, Imlau M
Optical Material Express 8(7), 1951-1967 (2018)
Nonlinear Optical Potassium Niobate Nanocrystals as Harmonic Markers: The Role of Precursors and Stoichiometry in Hydrothermal Synthesis
Wang Z, Kijatkin C, Urban A, Haase M, Imlau M and Kömpe K
Nanoscale, 10, 10713-10720 (2018)
2017
Ligand-induced type II interleukin-4 receptor dimers are sustained by rapid re-association within plasma membrane microcompartments
Richter D, Moraga I, Winkelmann H, Birkholz O, Wilmes S, Schulte M, Kraich M, Kenneweg H, Beutel O, Selenschik P, Paterok D, Gavutis M, Schmidt T, Garcia KC, Müller TD, Piehler J
Nat Commun, 8, 15976 (2017)
Magnetic control of cellular processes using biofunctional nanoparticles
Monzel C, Vicario C, Piehler J, Coppey M, Dahan M
Chemical science, 8, 7330-7338 (2017)
Engineered Ferritin for Magnetogenetic Manipulation of Proteins and Organelles Inside Living Cells
Liße D, Monzel C, Vicario C, Manzi J, Maurin I, Coppey M, Piehler J, Dahan M
Advanced materials, 29, 1700189 (2017)
Surrogate Wnt agonists that phenocopy canonical Wnt and beta-catenin signalling
Janda CY, Dang LT, You C, Chang J, de Lau W, Zhong ZA, Yan KS, Marecic O, Siepe D, Li X, Moody JD, Williams BO, Clevers H, Piehler J, Baker D, Kuo CJ, Garcia KC
Nature, 545, 234-237 (2017)
Binding of interferon reduces the force of unfolding for interferon receptor 1
Chuartzman SG, Nevo R, Waichman S, Shental D, Piehler J, Levy Y, Reich Z, Kapon R
PLoS One, 12, e0175413 (2017)
STAT2 is an essential adaptor in USP18-mediated suppression of type I interferon signaling
Arimoto KI, Löchte S, Stoner SA, Burkart C, Zhang Y, Miyauchi S, Wilmes S, Fan JB, Heinisch JJ, Li Z, Yan M, Pellegrini S, Colland F, Piehler J, Zhang DE
Nature structural & molecular biology, 24, 279-289 (2017)
ER residency of the ceramide phosphoethanolamine synthase SMSr relies on homotypic oligomerization mediated by its SAM domain
Cabukusta B, Kol M, Kneller L, Hilderink A, Bickert A, Mina JG, Korneev S, Holthuis JC
Sci Rep, 7, 41290 (2017)
Diverting CERT-mediated ceramide transport to mitochondria triggers Bax-dependent apoptosis
Jain A, Beutel O, Ebell K, Korneev S, and Holthuis JC
J Cell Sci 130, 360-371 (2017)
Switching head group selectivity in mammalian sphingolipid biosynthesis by active-site-engineering of sphingomyelin synthases
Kol M, Panatala R, Nordmann M, Swart L, van Suijlekom L, Cabukusta B, Hilderink A, Grabietz T, Mina JGM, Somerharju P, Korneev S, Tafesse FG, and Holthuis JC
J Lipid Res, 58, 962-973 (2017)
Nonlinear Diffuse fs-Pulse Reflectometry of Harmonic Upconversion Nanoparticles
Kijatkin C, Eggert J, Bock S, Berben D, Oláh L, Szaller Z, Kis Z and Imlau M
Photonics, 4(1), 11 (2017)
2016
Drosophila neprilysins control insulin signaling and food intake via cleavage of regulatory peptides
Hallier B, Schiemann R, Cordes E, Vitos-Faleato J, Walter S, Heinisch JJ, Malmendal A, Paululat A, Meyer H
Elife, (2016) Dec 6;5:e19430
Monitoring Changes in the Oligomeric State of a Candidate Endoplasmic Reticulum (ER) Ceramide Sensor by Single-molecule Photobleaching
Cabukusta B, Köhlen JA, Richter CP, You C, Holthuis JC
J Biol Chem, 291(47):24735–24746 (2016)
Functional protein micropatterning for drug design and discovery
You, C, and Piehler, J
Expert opinion on drug discovery, 11, 105-119 (2016)
Receptor dimer stabilization by hierarchical plasma membrane microcompartments regulates cytokine signaling
You C, Marquez-Lago TT, Richter CP, Wilmes S, Moraga I, Garcia KC, Leier A, Piehler J
Science advances, 2, e1600452 (2016)
Functional interplay between SA1 and TRF1 in telomeric DNA binding and DNA-DNA pairing
Lin J, Countryman P, Chen H, Pan H, Fan Y, Jiang Y, Kaur P, Miao W, Gurgel G, You C, Piehler J, Kad NM, Riehn R, Opresko PL, Smith S, Tao YJ, Wang H.
Nucleic acids research, 44, 6363-6376 (2016)
Bioinspired monolithic polymer microsphere arrays as generically anti-adhesive surfaces
Eichler-Volf A, Kovalev A, Wedeking T, Gorb EV, Xue L, You C, Piehler J, Gorb SN, Steinhart M
Bioinspiration & biomimetics, 11, 025002 (2016)
Engineered Upconversion Nanoparticles for Resolving Protein Interactions inside Living Cells
Drees C, Raj AN, Kurre R, Busch KB, Haase M, Piehler J
Angew Chem Int Ed Engl, 55, 11668-11672 (2016)
Single molecule super-resolution imaging of proteins in living Salmonella enterica using self-labelling enzymes
Barlag B, Beutel O, Janning D, Czarniak F, Richter CP, Kommnick C, Göser V, Kurre R, Fabiani F, Erhardt M, Piehler J, Hensel M
Scientific reports, 6, 31601 (2016)
Structure of the Tuberous Sclerosis Complex 2 (TSC2) N Terminus Provides Insight into Complex Assembly and Tuberous Sclerosis Pathogenesis
Zech R, Kiontke S, Mueller U, Oeckinghaus A, Kümmel D
J Biol Chem, 291, 20008 (2016)
The N-terminus of the floral Arabidopsis TGA transcription factor PERIANTHIA mediates redox-sensitive DNA-binding
Gutsche N and Zachgo S
PlosOne, 29; 11(4):e0153810 (2016)
